ArticleScientific reports2018
Association Between Serum Aluminum Level and Uremic Pruritus in Hemodialysis Patients.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Patient-Reported Outcome Measures in CKD-Associated Pruritus: A Systematic Review.Kidney medicine · 2025Review
- The role of blood purification therapies in the treatment of chronic kidney disease-associated pruritus: a systematic review.Clinical kidney journal · 2024Review
- Bone aluminum accumulation in the current era.Jornal brasileiro de nefrologia · 2024Article
- Article
- Assessing Cross-Sectional Association of Uremic Pruritus with Serum Heavy Metal Levels: A Single-Center Study.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Blood Aluminum Levels in Patients with Hemodialysis and Peritoneal Dialysis.International journal of environmental research and public health · 2022Observational
- Obstacles to Early Diagnosis and Treatment of Pruritus in Patients with Chronic Kidney Disease: Current Perspectives.International journal of nephrology and renovascular disease · 2022Review
- Chronic Kidney Disease-Associated Pruritus: A Glance at Novel and Lesser-Known Treatments.Cureus · 2022Review
- Chronic Kidney Disease-Associated Pruritus.Toxins · 2021Review
- Review
- Therapeutic effect of intravenous sodium thiosulfate for uremic pruritus in hemodialysis patients.Renal failure · 2020Article
- Practical considerations for performing regional anesthesia: lessons learned from the COVID-19 pandemic.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Review
- Sleep disturbance among Malaysian patients with end-stage renal disease with pruritus.BMC nephrology · 2019Article
- Western and complementary alternative medicine treatment of uremic pruritus: A literature review.Tzu chi medical journalReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Uremic pruritus (UP) is a common symptom in patients undergoing hemodialysis (HD). The pathogenesis of UP is complex. Aluminum (Al) is a common metal and is toxic to patients undergoing HD. Al is also a known human allergen which can induce immune reactions. However, the correlation between Al and UP remains unclear in dialysis patients. A total of 866 patients on maintenance HD were enrolled for analysis. The HD patients with higher serum Al levels had higher a prevalence of UP than those with lower serum Al levels. After adjusting for confounding variables, the serum Al level was significantly associated with UP. Overall, each 10-fold increase in serum Al level was associated with a 5.64-fold increase in the risk of developing UP in these subjects. The results of this cross-sectional study suggest that serum Al level may be associated with the development of UP in patients on maintenance HD.
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