Evidence map›Paper›PMID 30467322›Full record

ArticleScientific reports2018

Air trapping in usual interstitial pneumonia pattern at CT: prevalence and prognosis.

Bruno Hochhegger, Felipe Duenhas Sanches, Stephan Philip Leonhardt Altmayer, Gabriel Sartori Pacini, Matheus Zanon, Álvaro da Costa Batista Guedes, Guilherme Watte, Gustavo Meirelles, Marcelo Cardoso Barros, Edson Marchiori and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Biallelic LAMP3 variants in 5 families with interstitial lung disease: Evidence of a disease-gene association.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
    Article
  2. Article
  3. Microscopic Small Airway Abnormalities Identified in Early Idiopathic Pulmonary FibrosisAmerican journal of respiratory and critical care medicine · 2024
    Article
  4. Review
  5. Article
  6. Expiratory CT scanning in COVID-19 patients: can we add useful data?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  7. Review
  8. Dendriform pulmonary ossification in a patient with sickle cell disease.Lung India : official organ of Indian Chest Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Bruno HochheggerPathology Graduate Program, Federal University of Health Sciences of Porto Alegre - R. Sarmento Leite, 245, Porto Alegre, 90050170, Brazil. brunoho@ufcspa.edu.br.ORCID http://orcid.org/0000-0003-1984-4636
Felipe Duenhas SanchesPathology Graduate Program, Federal University of Health Sciences of Porto Alegre - R. Sarmento Leite, 245, Porto Alegre, 90050170, Brazil.
Stephan Philip Leonhardt AltmayerMedical Imaging Research Lab, LABIMED, Department of Radiology, Pavilhão Pereira Filho Hospital, Irmandade Santa Casa de Misericórdia de Porto Alegre - Av, Independência, 75, Porto Alegre, 90020160, Brazil.
Gabriel Sartori PaciniMedical Imaging Research Lab, LABIMED, Department of Radiology, Pavilhão Pereira Filho Hospital, Irmandade Santa Casa de Misericórdia de Porto Alegre - Av, Independência, 75, Porto Alegre, 90020160, Brazil.ORCID http://orcid.org/0000-0002-4822-7082
Matheus ZanonMedical Imaging Research Lab, LABIMED, Department of Radiology, Pavilhão Pereira Filho Hospital, Irmandade Santa Casa de Misericórdia de Porto Alegre - Av, Independência, 75, Porto Alegre, 90020160, Brazil.ORCID http://orcid.org/0000-0001-7851-5125
Álvaro da Costa Batista GuedesFederal University of Health Sciences of Porto Alegre - R. Sarmento Leite, 245, Porto Alegre, 90050170, Brazil.
Guilherme WatteMedical Imaging Research Lab, LABIMED, Department of Radiology, Pavilhão Pereira Filho Hospital, Irmandade Santa Casa de Misericórdia de Porto Alegre - Av, Independência, 75, Porto Alegre, 90020160, Brazil.
Gustavo MeirellesGrupo Fleury, Imaging - Av. João Pedro Cardoso, 158, São Paulo, 01333910, Brazil.
Marcelo Cardoso BarrosDepartment of Radiology, Pontificia Universidade Católica do Rio Grande do Sul - Av. Ipiranga 6690, Porto Alegre, RS, 90619900, Brazil.
Edson MarchioriDepartment of Radiology, Federal University of Rio de Janeiro Medical School - Av. Carlos Chagas Filho, 373, Rio de Janeiro, 21941902, Brazil.
Adalberto Sperb RubinMedical Imaging Research Lab, LABIMED, Department of Radiology, Pavilhão Pereira Filho Hospital, Irmandade Santa Casa de Misericórdia de Porto Alegre - Av, Independência, 75, Porto Alegre, 90020160, Brazil.
Universidade Federal de Ciências da Saúde de Porto Alegre · BRFleury S.A. (Brazil) · BRPontifícia Universidade Católica do Rio Grande do Sul · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to evaluate the presence of air trapping in patients with idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILDs) (non-IPF), showing the radiological pattern of usual interstitial pneumonia (UIP). Retrospectively, we included 69 consecutive patients showing the typical UIP pattern on computed tomography (CT), and 15 final diagnosis of IPF with CT pattern "inconsistent with UIP" due to extensive air trapping. Air trapping at CT was assessed qualitatively by visual analysis and quantitatively by automated-software. In the quantitative analysis, significant air trapping was defined as >6% of voxels with attenuation between -950 to -856 HU on expiratory CT (expiratory air trapping index [ATIexp]) or an expiratory to inspiratory (E/I) ratio of mean lung density >0.87. The sample comprised 51 (60.7%) cases of IPF and 33 (39.3%) cases of non-IPF ILD. Most patients did not have air trapping (E/I ratio ≤0.87, n = 53, [63.1%]; ATIexp ≤6%, n = 45, [53.6%]). Air trapping in the upper lobes was the only variable distinguishing IPF from non-IPF ILD (prevalence, 3.9% vs 33.3%, p < 0.001). In conclusion, air trapping is common in patients with ILDs showing a UIP pattern on CT, as determined by qualitative and quantitative evaluation, and should not be considered to be inconsistent with UIP. On subjective visual assessment, air trapping in the upper lobes was associated with a non-IPF diagnoses.

Indexed as

AgedDiagnosis, DifferentialFemaleHumansIdiopathic Pulmonary FibrosisLungLung Diseases, InterstitialMaleMiddle AgedPrevalencePrognosisRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID30467322
PMCPMC6250722
OpenAlexW2901498526

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.