Evidence map›Paper›PMID 30467293›Full record

ArticleMolecules (Basel, Switzerland)2018

Cytisine-Pterocarpan-Derived Compounds: Biomimetic Synthesis and Apoptosis-Inducing Activity in Human Breast Cancer Cells.

Ting-Ting Peng, Xuan-Rong Sun, Ren-Hao Liu, Lu-Xia Hua, Dong-Ping Cheng, Bin Mao, Xing-Nuo Li

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Identification of Anti-Proliferative Compounds fromMolecules (Basel, Switzerland) · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ting-Ting PengCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. pengtingting1993@163.com.
Xuan-Rong SunCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China. sunxr@zjut.edu.cn.ORCID 0000-0001-5414-9300
Ren-Hao LiuCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. liurenhao1994@outlook.com.
Lu-Xia HuaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. hlhua94@163.com.
Dong-Ping ChengCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. chengdp@zjut.edu.cn.
Bin MaoCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China. maob@zjut.edu.cn.
Xing-Nuo LiCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. li_xingnuo@163.com.

Funding

National Natural Science Foundation of China NO. 81502941Zhejiang Provincial Natural Science Foundation of China NO. LY16H300006
6 · The paper itself

Abstract

Cytisine-pterocarpan-derived compounds were biomimetically synthesized with (-)-cytisine and (-)-maackiain via a

Indexed as

AlkaloidsAnimalsAzocinesbcl-2-Associated X ProteinBiological MimicryBreast NeoplasmsCell Line, TumorCell ProliferationCell SurvivalCytochromes cFemaleHeterocyclic Compounds, 2-RingHumansMCF-7 CellsMiceMitochondriaAlkaloidsAzocinesBAX protein, humanbcl-2-Associated X ProteincytisineCytochromes cHeterocyclic Compounds, 2-RingProto-Oncogene Proteins c-bcl-2PterocarpansQuinolizidine AlkaloidsQuinolizinesbiomimetic synthesisbreast cancercytisine-pterocarpan derived compoundsmitochondrion-mediated apoptosis

Identifiers

PMID30467293
PMCPMC6321416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.