ArticleAJNR. American journal of neuroradiology2019
Differences in the Calculated Transvenous Pressure Drop between Chronic Hydrocephalus and Idiopathic Intracranial Hypertension.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Calvarial Bloom Biomechanics: Dural Tension Governing Cranial Form.Clinical anatomy (New York, N.Y.) · 2026Review
- CSF production rate, resistance to reabsorption, and intracranial pressure: a systematic review and meta-analysis.Brain communications · 2025Review
- Modelling of the dilated sagittal sinuses found in multiple sclerosis suggests increased wall stiffness may be a contributing factor.Scientific reports · 2022Article
- Mathematical modelling of the CSF system: effects of microstructures and posture on optic nerve subarachnoid space dynamics.Fluids and barriers of the CNS · 2022Article
- Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping.Scientific reports · 2022Article
- Transmantle and transvenous pressure gradients in cerebrospinal fluid disorders.Neurosurgical review · 2022Review
- Combined accuracy of optic nerve sheath diameter, strain ratio, and shear wave elastography of the optic nerve in patients with idiopathic intracranial hypertension.Ultrasonography (Seoul, Korea) · 2022Article
- The incidence of obesity, venous sinus stenosis and cerebral hyperaemia in children referred for MRI to rule out idiopathic intracranial hypertension at a tertiary referral hospital: a 10 year review.Fluids and barriers of the CNS · 2020Article
- The incidence of significant venous sinus stenosis and cerebral hyperemia in childhood hydrocephalus: prognostic value with regards to differentiating active from compensated disease.Fluids and barriers of the CNS · 2020Article
- Intracranial pressure elevation alters CSF clearance pathways.Fluids and barriers of the CNS · 2020Article
- The year in review: progress in brain barriers and brain fluid research in 2018.Fluids and barriers of the CNS · 2019Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeChronic hydrocephalus is associated with dilated ventricles despite a normal intracranial pressure. In idiopathic intracranial hypertension, the ventricles are normal despite an elevated intracranial pressure. This apparent paradox has largely remained unexplained. It is suggested that a pressure difference between the superficial and deep venous territories of the brain could account for the variation between the 2 diseases. The purpose of this paper is to investigate the cause of this pressure difference. MATERIALS AND
methodsUsing MR phase-contrast imaging, we calculated the hydraulic diameters of the sagittal and straight sinuses in 21 patients with hydrocephalus, 20 patients with idiopathic intracranial hypertension, and 20 age-matched controls. The outflow resistance of each sinus was estimated using the Poiseuille equation. The outflow pressure was estimated using the flow data. A smaller subset of the patients with hydrocephalus had these studies repeated after successful shunt insertion.
resultsIn hydrocephalus, the sagittal sinuses were 21% smaller than those in controls (
conclusionsThere is a transvenous pressure difference in hydrocephalus that is absent in idiopathic intracranial hypertension. This difference is eliminated by shunt insertion. The findings may have a bearing on ventricular dilation.
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