Evidence map›Paper›PMID 30467218›Full record

ArticleAJNR. American journal of neuroradiology2018

Abnormal Cerebral Perfusion Profile in Older Adults with HIV-Associated Neurocognitive Disorder: Discriminative Power of Arterial Spin-Labeling.

J Narvid, D McCoy, S M Dupont, A Callen, D Tosun, J Hellmuth, V Valcour

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

J NarvidFrom the Departments of Radiology and Biomedical Imaging (J.N., D.M., S.M.D., A.C., D.T.) jared.narvid@ucsf.edu.ORCID 0000-0002-2887-4231
D McCoyFrom the Departments of Radiology and Biomedical Imaging (J.N., D.M., S.M.D., A.C., D.T.).ORCID 0000-0003-2425-1923
S M DupontFrom the Departments of Radiology and Biomedical Imaging (J.N., D.M., S.M.D., A.C., D.T.).ORCID 0000-0001-9659-7056
A CallenFrom the Departments of Radiology and Biomedical Imaging (J.N., D.M., S.M.D., A.C., D.T.).ORCID 0000-0003-2315-7767
D TosunFrom the Departments of Radiology and Biomedical Imaging (J.N., D.M., S.M.D., A.C., D.T.).ORCID 0000-0001-8644-7724
J HellmuthNeurology (J.H., V.V.), University of California at San Francisco, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California.ORCID 0000-0002-7577-4196
V ValcourNeurology (J.H., V.V.), University of California at San Francisco, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California.ORCID 0000-0003-1981-4832
Laboratoire d’Imagerie Biomédicale · FRSan Francisco General Hospital · US

Funding

Machine learning to distinguish HAND from Alzheimer's disease in HIV over age 60R01MH113406 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POHL, KILIAN MARIA, VALCOUR, VICTOR · 2017 to 2021
$5.5M
Midcareer Mentoring Award for Patient-Oriented Research in HIV and CognitionK24MH098759 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VALCOUR, VICTOR · 2013 to 2017
$887k
Defining the clinical utility of CSF biomarkers of neurodegeneration in HIV+ eldersK23MH114724 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HELLMUTH, JOANNA · 2017 to 2020
$796k
NIMH NIH HHS K23 MH114724NIMH NIH HHS K24 MH098759NIMH NIH HHS R01 MH113406
6 · The paper itself

Abstract

background and purposeThe aging HIV-infected (HIV MATERIALS AND

methodsCBF data from the UCSF HIV Over 60 Cohort and the Alzheimer Disease Neuroimaging Initiative were retrospectively evaluated to identify 19 HIV

resultsWhen we accounted for age, education, sex, and vascular risk factors, the HIV

conclusionsThis study found specific CBF patterns associated with HIV status despite viral suppression-data that should animate further investigations into the pathobiologic basis of vascular and cognitive abnormalities in HIV-associated neurocognitive disorders.

Indexed as

AgedAIDS Dementia ComplexBrainCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingRetrospective StudiesSpin LabelsSpin Labels

Identifiers

PMID30467218
PMCPMC6748330
OpenAlexW2901970435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.