Evidence map›Paper›PMID 30467170›Full record

ArticleScience (New York, N.Y.)2018

Molecular to organismal chirality is induced by the conserved myosin 1D.

G Lebreton, C Géminard, F Lapraz, S Pyrpassopoulos, D Cerezo, P Spéder, E M Ostap, S Noselli

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Elucidating chiral myosin-induced actin dynamics: From single-filament behavior to collective structures.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Contractile forces direct the chiral swirling of minimal cell collectives.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Coupling between the lever arm and active site via an N-terminal extension tunes force sensitivity in the myosin-1 family.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Gliding direction ofBiophysics and physicobiology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

G LebretonUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID 0000-0002-5493-6176
C GéminardUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID 0000-0002-0018-9566
F LaprazUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID 0000-0001-9209-2018
S PyrpassopoulosPennsylvania Muscle Institute and the Center for Engineering Mechanobiology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
D CerezoUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.
P SpéderUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID 0000-0002-2934-5841
E M OstapPennsylvania Muscle Institute and the Center for Engineering Mechanobiology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
S NoselliUniversité Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France. noselli@unice.fr.ORCID 0000-0002-7296-324X

Funding

Molecular function of Myosin-lR37GM057247 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI OSTAP, E. MICHAEL · 2016 to 2025
$5.3M
NIGMS NIH HHS R37 GM057247
6 · The paper itself

Abstract

The emergence of asymmetry from an initially symmetrical state is a universal transition in nature. Living organisms show asymmetries at the molecular, cellular, tissular, and organismal level. However, whether and how multilevel asymmetries are related remains unclear. In this study, we show that

Indexed as

Models, MolecularActin CytoskeletonAnimalsDrosophila melanogasterDrosophila ProteinsIsomerismLarvaMyosin Type IMyosin Type VProtein Domainsdidum protein, DrosophilaDrosophila ProteinsMyo31DF protein, DrosophilaMyosin Type IMyosin Type V

Identifiers

PMID30467170
PMCPMC6698710

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.