ArticleHead & face medicine2018
Antinuclear antibody and rheumatoid factor positivity in temporomandibular disorders.
Article in Head & face medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Associations of inflammatory polyarthritis with clinical and radiological findings of temporomandibular disorders.Acta odontologica Scandinavica · 2024Article
- Etiologic Factors of Temporomandibular Disorders: A Systematic Review of Literature Containing Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) from 2018 to 2022.Healthcare (Basel, Switzerland) · 2024Review
- Does physical activity level have an impact on long-term treatment response in temporomandibular disorders: protocol for a prospective study.BMC oral health · 2022Article
- Evaluation of IL-1β and CRP mRNA expression levels by RT-PCR in postorthodontic treatment patients with temporomandibular joint disorders: a cross-sectional Study.Journal of International Society of Preventive & Community DentistryArticle
- Exploring the predictive power of antinuclear antibodies and Rheumatoid factor correlations in anticipating therapeutic outcomes for female patients with coexisting Sjögren's syndrome and Rheumatoid arthritis.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo investigate the differences in clinical characteristics and long-term treatment outcomes according to antinuclear antibody(ANA) and rheumatoid factor(RF) positivity and the correlation between pain-related and hematological indices in temporomandibular disorders(TMD) patients.
methodsClinical examinations were done following the Research Diagnostic Criteria for TMD in 257 patients. Comprehensive screening along with psychological and hematological evaluations (ANA, RF, complete blood cell count, C-reactive protein[CRP] and erythrocyte sedimentation rate[ESR]) were conducted. Clinical characteristics and treatment outcomes were statistically compared between ANA/RF positive and negative groups.
resultsThirty-nine patients showed ANA/RF positivity. Male patients had smaller comfortable mouth opening(CMO)(p = 0.033) and maximum mouth opening(MMO)(p = 0.016) ranges with more painful neck muscles on palpation when RF/ANA positive. Pain duration, intensity, disability days and psychological distress levels were also higher in RF/ANA positive male patients. Significant correlation was shown in ESR with pain duration(p < 0.05) and numeric rating scale(NRS) before treatment(p < 0.05), CRP with NRS before treatment(p < 0.01), and red blood cell (RBC) with pain intensity(p < 0.05), NRS before treatment(p < 0.01), CMO(p < 0.01), pain on palpation of cervical muscles(p < 0.01), CMO(p < 0.05), and MMO(p < 0.05) 6 months after treatment.
conclusionsThese results may point towards a nonspecific autoimmune disposition in a subgroup of TMD patients. RF and ANA could be considered as a screening test for the detection of autoimmune phenomena in TMD.
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