Evidence map›Paper›PMID 30466432›Full record

ArticleBMC veterinary research2018

Methionine to cystine ratio in the total sulfur amino acid requirements and sulfur amino acid metabolism using labelled amino acid approach for broilers.

Letícia G Pacheco, Nilva K Sakomura, Rafael M Suzuki, Juliano C P Dorigam, Gabriel S Viana, Jaap Van Milgen, Juliana C Denadai

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Canola Meal: A Sustainable Protein Source for Poultry Diets.Animals : an open access journal from MDPI · 2025
    Review
  4. Amino Acid Nutrition in Poultry: A Review.Animals : an open access journal from MDPI · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Engineered FungusJournal of fungi (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Letícia G PachecoDepartment of Animal Science, Unesp, Jaboticabal, SP, Brazil. legrazy@gmail.com.ORCID http://orcid.org/0000-0002-7803-6746
Nilva K SakomuraDepartment of Animal Science, Unesp, Jaboticabal, SP, Brazil.
Rafael M SuzukiDepartment of Animal Science, Unesp, Jaboticabal, SP, Brazil.
Juliano C P DorigamEvonik Nutrition & Care GmbH, Hanau, Germany.
Gabriel S VianaDepartment of Animal Science, Unesp, Jaboticabal, SP, Brazil.
Jaap Van MilgenINRA, Agrocampus Ouest, Rennes, France.
Juliana C DenadaiDepartment of Animal Science, Unesp, Botucatu, SP, Brazil.
Núcleo de Pesquisas Aplicadas (Brazil) · BREvonik (Germany) · DEInstitut Agro Rennes-Angers · FRUniversidade Estadual Paulista (Unesp) · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/25761-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/25717-0
6 · The paper itself

Abstract

backgroundAssuming that part of Methionine (Met) is converted into Cystine (Cys), but ignoring the rates with which such phenomenon occurs may lead to an excessive supply of Met in poultry diets. Such inconvenient could be easily avoided with the knowledge of the ideal Met:Cys/Total sulfur amino acids (TSAA) ratio and the rates of Met conversion into Cys.

resultsMet sources did not affect performance. Met:Cys/TSAA ideal ratio was determined using curvilinear-plateau regression model. Both optimum body weight gain and feed conversion ratio were estimated in 1007 g/day and 1.49, respectively, at 52% Met/TSAA ratio. Feed intake was not affected by Met:Cys/TSAA ratios. In the labelled amino acid assay, the rates with which Met was converted into Cys ranged from 27 to 43% in response to changes in Met:Cys/TSAA ratios, being higher at 56:44.

conclusionBased on performance outcomes, the minimum concentration of Met relative to Cys in diets for broilers from 14 to 28 d of age based on a TSAA basis, is 52% (52:48 Met:Cys/TSAA). The outcomes from labelled amino acid assay indicate that highest the Met supply in diets, the highest is its conversion into Cys.

Indexed as

ChickensAmino Acids, SulfurAnimal FeedAnimalsCystineIsotope LabelingMaleMethionineNitrogen IsotopesNutritional RequirementsRandom AllocationAmino Acids, SulfurCystineMethionineNitrogen IsotopesCystineMethionine conversionMethionine cycleStable isotopesSulfur amino acids

Identifiers

PMID30466432
PMCPMC6251137
OpenAlexW2901812059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.