ArticleBMC nephrology2018
Glomerular filtration rate: new age- and gender- specific reference ranges and thresholds for living kidney donation.
Article in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society.European journal of nutrition · 2023Pooled it
- Health status of living kidney donors and attitude toward donation-Results from the German Living Donor Registry (SOLKID-GNR).Frontiers in medicine · 2026Article
- Article
- Prevalence of reduced eGFR in European adults using KDIGO and age-adapted eGFR thresholds.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Screening Using Chronic Kidney Disease Epidemiology Collaboration 2021 Equation Glomerular Filtration Rate Underestimates in Living Kidney Donors Compared With Measurement of Glomerular Filtration Rate.Transplantation direct · 2025Article
- Quantifying clinical and genetic factors influencing rate and severity of autosomal dominant tubulointerstitial kidney disease progression.Journal of pharmacokinetics and pharmacodynamics · 2025Article
- Establishment of adult reference interval of oxalate in spot urine using real-world data.European journal of medical research · 2025Article
- Perfluorooctanoic acid serum concentrations and half-lives in a community exposed to contaminated drinking water in New York State.Journal of exposure science & environmental epidemiology · 2025Article
- Effect of truncating blood sampling in measuring glomerular filtration rate.American journal of nuclear medicine and molecular imaging · 2025Article
- Age- and sex-specific reference values for CT-based low skeletal muscle quantity and quality in healthy living kidney donors.Frontiers in physiology · 2025Article
- Reference Ranges for All: Implementing Reference Ranges for Transgender and Nonbinary Patients.Applied clinical informatics · 2024Article
- The impact of population ageing on the burden of chronic kidney disease.Nature reviews. Nephrology · 2024Review
- Tumour lysis syndrome.Nature reviews. Disease primers · 2024Review
- Brain-body mechanisms contribute to sexual dimorphism in amyotrophic lateral sclerosis.Nature reviews. Neurology · 2024Review
- Consequences of kidney donation by age in Japanese living kidney donors: a single-center study.Clinical and experimental nephrology · 2024Observational
- Evaluation of gender differences in the pharmacokinetics of oral zileuton nanocrystalline formulation using a rat model.International journal of pharmaceutics: X · 2024Article
- Current perspective on circadian function of the kidney.American journal of physiology. Renal physiology · 2024Review
- Gender Differences in Pharmacokinetics: A Perspective on Contrast Agents.ACS pharmacology & translational science · 2024Review
- Feasibility and reliability of measured glomerular filtration rate with [I125]-iothalamate among young adults with mild-to-moderate cerebral palsy.Frontiers in medicine · 2024Article
- Longitudinal Trajectories of Estimated Glomerular Filtration Rate in a European Population of Living Kidney Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a need for a large, contemporary, multi-centre series of measured glomerular filtration rates (mGFR) from healthy individuals to determine age- and gender-specific reference ranges for GFR. We aimed to address this and to use the ranges to provide age- and gender-specific advisory GFR thresholds considered acceptable for living kidney donation.
methodsIndividual-level data including pre-donation mGFR from 2974 prospective living kidney donors from 18 UK renal centres performed between 2003 and 2015 were amalgamated. Age- and gender-specific GFR reference ranges were determined by segmented multiple linear regression and presented as means ± two standard deviations.
resultsMales had a higher GFR than females (92.0 vs 88.1 mL/min/1.73m
conclusionsThese data suggest that GFR declines after 35 years of age, and the decline is faster in females. A significant proportion of the healthy population over 60 years of age have a GFR < 60 mL/min/1.73m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.