Evidence map›Paper›PMID 30465878›Full record

ReviewBrain, behavior, and immunity2019

The role of Th17 cells in the pathophysiology of pregnancy and perinatal mood and anxiety disorders.

Lauren M Osborne, Amitoj Brar, Sabra L Klein

Open access · greenAbstract readReview
In one paragraph

Review in Brain, behavior, and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Immune Cells in Preeclampsia.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. CD4Neurobiology of stress · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Circulating JKAP levels may correlate with postpartum anxiety and depression through its interaction with T helper 17 cells.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Article
  16. Pregnancy Outcomes in Hidradenitis Suppurativa Patients.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  17. Article
  18. The immune phenotype of perinatal anxiety.Brain, behavior, and immunity · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lauren M OsborneWomen's Mood Disorders Center, Departments of Psychiatry & Behavioral Sciences, and of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States. Electronic address: lmosborne@jhmi.edu.
Amitoj BrarWomen's Mood Disorders Center, Departments of Psychiatry & Behavioral Sciences, and of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States.
Sabra L KleinW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Johns Hopkins University · US

Funding

Biological Mechanisms of Perinatal AnxietyK23MH110607 · NIMH · JOHNS HOPKINS UNIVERSITY · PI OSBORNE, LAUREN M · 2017 to 2021
$985k
NIMH NIH HHS K23 MH110607
6 · The paper itself

Abstract

T cells play a key role in adaptive immune responses, and shifts among T cell classes occur in normal pregnancy. There is evidence for the role of T

Indexed as

AffectAnxiety DisordersAutoimmune DiseasesCytokinesDepressionDepressive DisorderFemaleHumansPostnatal CarePregnancyTh17 CellsT-Lymphocytes, RegulatoryCytokinesAnxietyDepressionPerinatalPregnancyT(H)17T(reg)

Identifiers

PMID30465878
PMCPMC6359933
OpenAlexW2901806432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.