Evidence map›Paper›PMID 30465636›Full record

ArticleCognitive neuroscience

Prefrontal transcranial direct current stimulation (tDCS) enhances behavioral and EEG markers of proactive control.

Megan Boudewyn, Brooke M Roberts, Eda Mizrak, Charan Ranganath, Cameron S Carter

Abstract read
In one paragraph

Article in Cognitive neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megan Boudewyna Department of Psychiatry and Behavioral Sciences , UC Davis Medical Center, University of California , Davis , USA.
Brooke M Robertsa Department of Psychiatry and Behavioral Sciences , UC Davis Medical Center, University of California , Davis , USA.
Eda Mizraka Department of Psychiatry and Behavioral Sciences , UC Davis Medical Center, University of California , Davis , USA.
Charan Ranganatha Department of Psychiatry and Behavioral Sciences , UC Davis Medical Center, University of California , Davis , USA.
Cameron S Cartera Department of Psychiatry and Behavioral Sciences , UC Davis Medical Center, University of California , Davis , USA.

Funding

PATHOPHYSIOLOGY OF COGNITIVE DISABILITY IN SCHIZOPHRENIAR01MH059883 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARTER, CAMERON S. · 2000 to 2017
$6.1M
NIMH NIH HHS R01 MH059883
6 · The paper itself

Abstract

This study examined the effects of stimulation targeting dorsolateral prefrontal cortex (DLPFC) on behavioral and neural oscillatory markers of proactive cognitive control in healthy adults. We hypothesized that active stimulation targeting the DLPFC would enhance proactive control compared to sham, leading to changes in the pattern of error rates and gamma-band power on the Dot Pattern Expectancy (DPX) task. We recorded EEG while participants completed the DPX, after receiving either 20 minutes of active DLPFC stimulation at 2 mA or sham stimulation in a counterbalanced within-participants design. The results showed significant tDCS-induced changes in the pattern of error rates on the DPX task indicative of enhanced proactive control, as well as predicted increases in gamma power associated with the engagement of proactive control. These results provide support for the role of DLPFC-mediated gamma activity in proactive cognitive control, and further, indicate that proactive control can be enhanced with non-invasive neurostimulation.

Indexed as

AdultExecutive FunctionFemaleGamma RhythmHumansMalePrefrontal CortexPsychomotor PerformanceTranscranial Direct Current StimulationYoung AdultEEGgammaproactive controltDCS

Identifiers

PMID30465636
PMCPMC6375081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.