Evidence map›Paper›PMID 30465216›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019

Socioeconomic status and risk of osteoporotic fractures and the use of DXA scans: data from the Danish population-based ROSE study.

T Holmberg, S Möller, M J Rothmann, J Gram, A P Herman, K Brixen, J S Tolstrup, M Høiberg, M Bech, K H Rubin

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01388244 (Risk-stratified Osteoporosis Strategy Evaluation Study), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01388244 nacompletednot on this map

Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE)

TypeinterventionalSponsorOdense University HospitalRan2010 to 2021Enrolled35,000ConditionsOsteoporosisArmsScreening, Control
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Socio-economic inequalities in fragility fracture incidence: a systematic review and meta-analysis of 61 observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
  2. Article
  3. The role of income and educational level as risk factors for atypical femur fractures: A Nationwide Danish Case-Cohort Study with Blinded Radiographic Review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  6. Healthcare and productivity cost of osteoporosis: a Danish register-based quasi-experimental study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  9. Association between socioeconomic deprivation and bone health status in the UK biobank cohort participants.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  13. Determinants of Bone Mineral Screening Behavior among Three Ethno-Cultural Groups of Women in Israel.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

T HolmbergNational Institute of Public Health, University of Southern Denmark, Studiestræde 6, DK-1355, Copenhagen K, Denmark. tho@niph.dk.ORCID http://orcid.org/0000-0002-4671-3810
S MöllerOPEN - Odense Patient Data Explorative Network, Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
M J RothmannDepartment of Endocrinology, Odense University Hospital, Odense, Denmark.
J GramDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
A P HermanDepartment of Endocrinology, Odense University Hospital, Odense, Denmark.
K BrixenOdense University Hospital, Odense, Denmark.
J S TolstrupNational Institute of Public Health, University of Southern Denmark, Studiestræde 6, DK-1355, Copenhagen K, Denmark.
M HøibergDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
M BechDepartment of Political Science, Aarhus University, Aarhus, Denmark.
K H RubinOPEN - Odense Patient Data Explorative Network, Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
University of Southern Denmark · DKAarhus University · DKOdense University Hospital · DK

Funding

INTERREG 4A JNR 08/4177Odense Universitetshospital JNR 11/5761Region of Sothern Denmark JNR 08/8133
6 · The paper itself

Abstract

There is a need of studies exploring the link between socioeconomic status and DXA scans and osteoporotic fracture, which was the aim of the present study. No differences in socioeconomic status and risk of osteoporotic fractures were found. However, women with further/higher education and higher income are more often DXA-scanned.

introductionLower socioeconomic status is known to be associated with a range of chronic conditions and with access to health care services. The link between socioeconomic status and the use of DXA scans and osteoporotic fracture, however, needs to be explored more closely. Therefore, the aim of this study was to examine the relationship between socioeconomic status and both DXA scan utilization and major osteoporotic fractures (MOF) using a population-based cohort of Danish women and national registers.

methodsThe study included 17,155 women (65-81 years) sampled from the Risk-stratified Osteoporosis Strategy Evaluation study (ROSE). Information on socioeconomic background, DXA scans, and MOFs was retrieved from national registers. Competing-risk regression analyses were performed. Mean follow-up was 4.8 years.

resultsA total of 4245 women had a DXA scan (24.7%) and 1719 (10.0%) had an incident MOF during follow-up. Analyses showed that women with basic education had a lower probability of undergoing DXA scans than women with further or higher education (greater than upper secondary education and vocational training education) (subhazard ratio (SHR) = 0.82; 95% CI 0.75-0.89, adjusted for age and comorbidity). Moreover, women with disposable income in the low and medium tertiles had a lower probability of undergoing DXA scans than women in the high-income tertile (SHR = 0.90; 95% CI 0.84-0.97 and SHR = 0.88, 95% CI 0.82-0.95, respectively, adjusted for age and comorbidity). No association between socioeconomic background and probability of DXA was found in adjusted analyses.

conclusionThe study found no differences in risk of osteoporotic fractures depending on socioeconomic status. However, women with further or higher education as well as higher income are more often DXA-scanned.

Indexed as

Social ClassAbsorptiometry, PhotonAgedAged, 80 and overComorbidityDenmarkEducational StatusFemaleFollow-Up StudiesHealthcare DisparitiesHealth Services AccessibilityHumansIncidenceIncomeOsteoporosis, PostmenopausalOsteoporotic FracturesDXA scanOsteoporotic fracturesSocioeconomic inequality in healthSocioeconomic statusWomen

Identifiers

PMID30465216
OpenAlexW2901921158

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.