Evidence map›Paper›PMID 30465143›Full record

SynthesisInternational urology and nephrology2019

Total parenteral nutrition versus early enteral nutrition after cystectomy: a meta-analysis of postoperative outcomes.

Shuxiong Zeng, Yongping Xue, Junjie Zhao, Anwei Liu, Zhensheng Zhang, Yinghao Sun, Chuanliang Xu

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. A Prospective Randomized Trial Comparing Jejunostomy and Nasogastric Feeding in Minimally Invasive McKeown Esophagectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Trial
  3. Article
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shuxiong ZengDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China.
Yongping XueDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China.
Junjie ZhaoDepartment of Urology, Yantai Yuhuangding Hospital, Yantai, Shandong, People's Republic of China.
Anwei LiuDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China.
Zhensheng ZhangDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China.
Yinghao SunDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China. sunyhsmmu@126.com.
Chuanliang XuDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, People's Republic of China. xuchuanliang@vip.126.com.
Second Military Medical University · CNChanghai Hospital · CNYuhuangding Hospital · CN

Funding

Medical Science and Technology Development Project of Shandong Province 2016WS0703National Natural Science Foundation of China 81802515Natural Science Foundation of Shandong Province ZR2016HL36Shanghai Sailing Program 18YF1422700Starting Foundation for Young Scientists of Second Military Medical University 2017QN11
6 · The paper itself

Abstract

backgroundThis study aimed to systematically summarize and analyze the current evidence regarding the effect of total parenteral nutrition (TPN) versus early enteral nutrition (EEN) on postoperative outcomes of cystectomy.

methodsA comprehensive search of online databases was conducted to identify comparative studies on the postoperative outcomes of patients receiving TPN and EEN after cystectomy. Our subsequent meta-analysis followed the PRISMA Protocol and the Cochrane Handbook.

resultsFive studies with 556 participants were included for meta-analysis. EEN was shown to have a significant effect on reducing the overall complications (odds ratio (OR) 0.52, 95% confidence interval (CI) 0.37-0.75, P < 0.01) and infectious complications (OR 0.32, 95% CI 0.21-0.49, P < 0.01) compared with TPN. Additionally, EEN saved €614-€3120 in costs compared to TPN. There were no significant differences between TPN and EEN groups regarding mortality rate (OR 0.47, 95% CI 0.06-3.51, P = 0.46), the incidence of postoperative ileus (OR 0.90, 95% CI 0.55-1.47, P = 0.68), length of hospital stay (mean difference (MD) 2.12, 95% CI - 0.15 to 4.40, P = 0.07), or time to resume a full diet (MD 1.31, 95% CI - 1.15 to 3.77, P = 0.30).

conclusionEEN was found to have a significant effect on reducing infectious complications and costs compared with TPN treatment after cystectomy. Remarkably, EEN had no significant impact on mortality incidence, postoperative ileus, length of hospital stay, or the time to resumption of full diet.

Indexed as

CystectomyEnteral NutritionHumansOutcome Assessment, Health CareParenteral Nutrition, TotalPostoperative CarePostoperative ComplicationsCystectomyEnteral nutritionMeta-analysisParenteral nutrition

Identifiers

PMID30465143
OpenAlexW2901489686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.