Evidence map›Paper›PMID 30465091›Full record

ArticleJournal of bone and mineral metabolism2019

Re-fracture and correlated risk factors in patients with osteoporotic vertebral fractures.

Xinling Ma, Haiou Xia, Jinhua Wang, Xiaoxiao Zhu, Fangyan Huang, Liuxue Lu, Lanyan He

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In one paragraph

Article in Journal of bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. MiR-148a-3p regulates the fracture healing process by targeting MAFB.Journal of orthopaedic surgery and research · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. The impact of chronic obstructive pulmonary disease on bone strength.Journal of bone and mineral metabolism · 2024
    Review
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  11. Article
  12. Review
  13. Article
  14. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xinling MaSchool of Nursing, Fudan University, Shanghai, 200032, China.
Haiou XiaSchool of Nursing, Fudan University, Shanghai, 200032, China. hsxia@fudan.edu.cn.
Jinhua WangYoujiang Medical University for Nationalities, Baise, 533000, China.
Xiaoxiao ZhuSchool of Nursing, Fudan University, Shanghai, 200032, China.
Fangyan HuangYoujiang Medical University for Nationalities, Baise, 533000, China.
Liuxue LuThe Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China.
Lanyan HeThe Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China.
Affiliated Hospital of Youjiang Medical University for Nationalities · CNFudan University · CNWest China Medical Center of Sichuan University · CN

Funding

Fuxing Nursing Scientific Research Fund of Fudan University FNF201708National Natural Science Foundation of China 815602390
6 · The paper itself

Abstract

Re-fracture risk is higher following osteoporotic fracture. However, there is no accurately reported rate of re-fracture incidence in southwest China. The purpose of this study was to describe the osteoporotic vertebral fracture (OVF) survival for re-fracture state and analyze the risk of re-fracture. This historical cohort study was conducted in four hospitals in southwest China. Patients aged ≥ 50 years (n = 586) with OVF who were supposed to receive anti-osteoporosis drugs after the fracture were included (2012-2017). Telephone follow-up and referring case files were used to estimate the survival for re-fracture and identify the determinants of re-fracture. A total of 555 patients completed the follow-up investigation. Overall, 285 patients experienced a re-fracture, and the longest follow-up investigation time was 72 months. The survival rates for re-fracture at 12 months, 24 months, 36 months, and 48 months were 82.0%, 71.5%, 61.7%, and 34.0%, respectively. The factors correlated with re-fracture hazard were advanced age [hazard ratio (HR) = 1.996], being female (HR = 1.342), smoking (HR = 1.435), history of hypertension (HR = 1.219) and diabetes (HR = 3.271), and persistence of taking anti-osteoporosis drugs after fracture [0-3 months, 4-6 months, 7-12 months, and more than 12 months (HR = 0.703)]. OVF patients with advanced age, who were female, smoked, had fracture with hypertension or diabetes, and who complied poorly with anti-osteoporosis drug treatment presented higher prevalence of re-fracture and low anti-osteoporosis adherence in southwest China. The management of anti-osteoporosis after fracture is necessary in this area.

Indexed as

AgedChinaCohort StudiesFemaleFollow-Up StudiesHumansMaleMultivariate AnalysisOsteoporotic FracturesProportional Hazards ModelsRisk FactorsSpinal FracturesAnti-osteoporosisOsteoporosisOsteoporotic vertebral fractureRe-fracture

Identifiers

PMID30465091
OpenAlexW2900812001

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.