Evidence map›Paper›PMID 30464749›Full record

ArticleFrontiers in psychiatry2018

Lower Choline Rate in the Left Prefrontal Cortex Is Associated With Higher Amount of Alcohol Use in Alcohol Use Disorder.

Rodrigo Stênio Moll de Souza, Marcos Rosa, Thaísa Malbar Rodrigues, Thayssa Dalla Costa Escobar, Emerson Leandro Gasparetto, Ester Miyuki Nakamura-Palacios

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Brain Structure and Function in Recovery.Alcohol research : current reviews · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rodrigo Stênio Moll de SouzaDepartment of Internal Medicine, Health Sciences Center, Federal University of Espírito Santo, Vitória, Brazil.
Marcos RosaDepartment of Internal Medicine, Health Sciences Center, Federal University of Espírito Santo, Vitória, Brazil.
Thaísa Malbar RodriguesDepartment of Internal Medicine, Health Sciences Center, Federal University of Espírito Santo, Vitória, Brazil.
Thayssa Dalla Costa EscobarHealth Sciences Center, University Hospital Cassiano Antônio de Moraes, Federal University of Espírito Santo, Vitória, Brazil.
Emerson Leandro GasparettoDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Ester Miyuki Nakamura-PalaciosBRAEN - Brazilian Research Group on Brain and Cognitive Engineering, Federal University of Espírito Santo, Vitória, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive and long-term alcohol consumption produce metabolic changes, such as of choline, in many brain regions in alcohol use disorder (AUD) and in non-AUD subjects as well. This study examined the association of choline proportion in the prefrontal cortex with pattern of alcohol use in AUD patients. The choline metabolite was acquired through a single voxel Proton Magnetic Resonance Spectroscopy (

Indexed as

1H MRSalcohol intakealcohol use disordercholineprefrontal

Identifiers

PMID30464749
PMCPMC6234763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.