Evidence map›Paper›PMID 30464617›Full record

ArticleCancer management and research2018

Interleukin-18 promoter genotype is associated with the risk of nasopharyngeal carcinoma in Taiwan.

Chung-Yu Huang, Wen-Shin Chang, Chia-Wen Tsai, Te-Chun Hsia, Te-Chun Shen, Da-Tian Bau, Hao-Ai Shui

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Association ofIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chung-Yu HuangGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Wen-Shin ChangTerry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, datian@mail.cmuh.org.tw.
Chia-Wen TsaiTerry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, datian@mail.cmuh.org.tw.
Te-Chun HsiaTerry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, datian@mail.cmuh.org.tw.
Te-Chun ShenTerry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, datian@mail.cmuh.org.tw.
Da-Tian BauTerry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, datian@mail.cmuh.org.tw.
Hao-Ai ShuiGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
China Medical University · TWAsia University · TWNational Defense Medical Center · TWTaoyuan Armed Forces General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence rate of nasopharyngeal carcinoma (NPC) has been documented to be high in Southeast Asia. Interleukin-18 (IL-18) is a multifunctional cytokine that augments interferon-γ production and acts as an important immunomediator in the development of several types of cancer. PATIENTS AND

methodsThis case-control study evaluated the role of

resultsThe CC genotype of the

conclusionThis study suggests that

Indexed as

genotypeIL-18nasopharyngeal carcinoma (NPC)polymorphismTaiwan

Identifiers

PMID30464617
PMCPMC6217138
OpenAlexW2899366621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.