Evidence map›Paper›PMID 30464566›Full record

ReviewDiabetes, metabolic syndrome and obesity : targets and therapy2018

COSMIC project: consensus on the objectives of the metabolic syndrome in clinic.

Juan Pedro-Botet, Juan F Ascaso, Vivencio Barrios, Alejandro De la Sierra, Javier Escalada, Jesús Millán, Jose M Mostaza, Pablo Pérez-Martínez, Xavier Pintó, Jordi Salas-Salvadó and 1 more

Abstract readReview
In one paragraph

Review in Diabetes, metabolic syndrome and obesity : targets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Review
  4. Article
  5. Mechanisms of Oxidative Stress in Metabolic Syndrome.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Atherogenic dyslipemia: the other pandemic, associated with diabesity.Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juan Pedro-BotetLipids and Vascular Risk Unit, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain, JPedrobotet@parcdesalutmar.cat.
Juan F AscasoEndocrinology and Nutrition Service, Hospital Clínico, Universitat de Valencia, Valencia, Spain.
Vivencio BarriosCardiology Service, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain.
Alejandro De la SierraInternal Medicine Service, Hospital Mutua de Terrassa, Department of Medicine, Universidad de Barcelona, Spain.
Javier EscaladaDepartment of Endocrinology and Nutrition, Clínica Universitaria de Navarra, IdiSNA.
Jesús MillánLipid Unit, Department of Internal Medicine, Hospital Universitario General Gregorio Marañón, Universidad Complutense, Madrid, Spain.
Jose M MostazaLipid and Arteriosclerosis Unit, Internal Medicine Service, Hospital Carlos III, Madrid, Spain.
Pablo Pérez-MartínezCIBEROBN "Physiopathology of Obesity and Nutrition", Carlos III Health Institute, Spain.
Xavier PintóCIBEROBN "Physiopathology of Obesity and Nutrition", Carlos III Health Institute, Spain.
Jordi Salas-SalvadóCIBEROBN "Physiopathology of Obesity and Nutrition", Carlos III Health Institute, Spain.
Pedro ValdivielsoInternal Medicine Service, Department of Medicine and Dermatology, Hospital Universitario Virgen de la Victoria, Málaga Biomedicine Institute (IBIMA), Universidad de Málaga, Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (MetS), a disorder with a high and growing prevalence, is a recognized risk factor for cardiovascular disease (CVD) and type 2 diabetes. It is a constellation of clinical and metabolic risk factors that include abdominal obesity, dyslipidemia, glucose intolerance, and hypertension. Unfortunately, MetS is typically underrecognized, and there is great heterogeneity in its management, which can hamper clinical decision-making and be a barrier to achieving the therapeutic goals of CVD and diabetes prevention. Although no single treatment for MetS as a whole currently exists, management should be targeted at treating the conditions contributing to it and possibly reversing the risk factors. All this justifies the need to develop recommendations that adapt existing knowledge to clinical practice in our healthcare system. In this regard, professionals from different scientific societies who are involved in the management of the different MetS components reviewed the available scientific evidence focused basically on therapeutic aspects of MetS and developed a consensus document to establish recommendations on therapeutic goals that facilitate their homogenization in clinical decision-making.

Indexed as

cardiovascular preventiondiabetes preventiondyslipidemiahypertensioninsulin resistanceobesity

Identifiers

PMID30464566
PMCPMC6217133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.