Evidence map›Paper›PMID 30464547›Full record

ArticleInfection and drug resistance2018

Noninvasive screening identifies patients at risk for spontaneous bacterial peritonitis caused by multidrug-resistant organisms.

Philip G Ferstl, Mona Müller, Natalie Filmann, Michael Hogardt, Volkhard Aj Kempf, Thomas A Wichelhaus, Christian M Lange, Johannes Vermehren, Stefan Zeuzem, Claudia Reinheimer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Philip G FerstlDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Mona MüllerDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Natalie FilmannInstitute of Biostatistics and Mathematical Modeling, University Hospital Frankfurt, Frankfurt am Main, Germany.
Michael HogardtUniversity Center for Infectious Diseases (UCI), University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Volkhard Aj KempfUniversity Center for Infectious Diseases (UCI), University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Thomas A WichelhausUniversity Center for Infectious Diseases (UCI), University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Christian M LangeDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Johannes VermehrenDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Stefan ZeuzemDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Claudia ReinheimerUniversity Center for Infectious Diseases (UCI), University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Oliver WaidmannDepartment for Internal Medicine I/Gastroenterology and Hepatology, University Hospital Frankfurt, Frankfurt am Main, Germany, philip.ferstl@kgu.de.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsSpontaneous bacterial peritonitis (SBP) is a severe complication of decompensated cirrhosis. The prevalence of multidrug-resistant organisms (MDROs) in patients with cirrhosis is increasing. Identification of patients at risk for SBP due to MDROs (ie, SBP with the evidence of MDROs or PATIENTS AND

methodsThis retrospective study was conducted at the liver center of the University Hospital Frankfurt, Germany. Between 2011 and 2016, patients with cirrhosis were included upon diagnosis of SBP and sample collection of aerobic/anaerobic ascitic cultures. Furthermore, the performance of at least one complete MDRO screening was mandatory for study inclusion.

resultsOf 133 patients diagnosed with SBP, 75 (56.4%) had culture-positive SBP and 22 (16.5%) had MDRO-SBP. Multidrug-resistant

conclusionMDRO screening may serve as a noninvasive diagnostic tool to identify patients at risk for MDRO-SBP. Patients with decompensated cirrhosis should be screened for MDROs from the first day of inpatient treatment onward.

Indexed as

antibiotic therapyascitesliver cirrhosismultidrug resistancescreening routine

Identifiers

PMID30464547
PMCPMC6223386
OpenAlexW2899393117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.