ArticleTherapeutics and clinical risk management2018
Balancing intubation time with postoperative risk in cardiac surgery patients - a retrospective cohort analysis.
Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05801679 (A Prospective Randomized Blinded Controlled Trial Comparing Clinical Outcomes in Cardiac Surgical Patients Who Receive Sugammadex vs. Placebo), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Randomized Blinded Controlled Trial Comparing Clinical Outcomes in Cardiac Surgical Patients Who Receive Sugammadex vs. Placebo
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Risk prediction models for prolonged mechanical ventilation following coronary artery bypass grafting surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Analgesic efficacy and risk of low-to-medium dose intrathecal morphine in patients undergoing cardiac surgery: An updated meta-analysis.Frontiers in medicine · 2022Pooled it
- Comparing Clinical Outcomes in Cardiac Surgical Patients Who Receive Sugammadex Versus Placebo: A Prospective Randomized Blinded Controlled Trial.Critical care explorations · 2026Trial
- Predictors of delayed extubation post-coronary artery bypass graft and its relationship with length of stay and in-hospital mortality in Jordan.Acute and critical care · 2026Article
- Nicotine Withdrawal Syndrome in Intensive Care Patients-Preventive and Therapeutic Implications.Medical sciences (Basel, Switzerland) · 2026Review
- Review
- Association of Plasma BDNF Concentration and Val66Met Polymorphism with Postoperative Delirium After Cardiac Surgery Under General Anesthesia with Cardiopulmonary Bypass.Journal of clinical medicine · 2025Article
- Sugammadex Safely Reduces Total Intubation Time in the Intensive Care Unit Following Coronary Artery Bypass Grafting (CABG) at a Real-World Community Hospital.Journal of clinical medicine · 2025Article
- A Scoping Review of Factors Associated with Delayed Extubation in Post Cardiac Surgery Patients.Vascular health and risk management · 2025Article
- Risk Factors of Prolonged Mechanical Ventilation in Post Coronary Artery Bypass Graft Patients: A Scoping Review.Journal of multidisciplinary healthcare · 2025Review
- Predictive Factors of Length of Stay in Intensive Care Unit after Coronary Artery Bypass Graft Surgery based on Machine Learning Methods.Archives of academic emergency medicine · 2025Article
- A novel nomogram for predicting prolonged mechanical ventilation after acute type A aortic dissection surgery: a retrospective study investigating the impact of ventilation duration on postoperative outcomes.Annals of medicine · 2024Article
- Clinical Outcomes and Risk Factors of Heart Transplantation Patients Experiencing Gastrointestinal Bleeding.Biomedicines · 2024Article
- Early administration of ketorolac after cardiac surgery and postoperative complications: Analysis of the MIMIC-IV database.Clinical and translational science · 2024Article
- Article
- Article
- Early identification of delayed extubation following cardiac surgery: Development and validation of a risk prediction model.Frontiers in cardiovascular medicine · 2022Article
- Hypotension after intensive care unit drop-off in adult cardiac surgery patients.World journal of critical care medicine · 2020Article
- Patient-ventilator asynchrony in conventional ventilation modes during short-term mechanical ventilation after cardiac surgery: randomized clinical trial.Multidisciplinary respiratory medicine · 2020Article
- The Efficacy of Inpatient vs. Home-Based Physiotherapy Following Coronary Artery Bypass Grafting.International journal of environmental research and public health · 2018Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIntubation time in patients undergoing cardiac surgery may be associated with increased mortality and morbidity. Premature extubation can have serious adverse physiological consequences. The aim of this study was to determine the influence of intubation time on morbidity and mortality in patients undergoing cardiac surgery.
methodsWe performed a retrospective analysis of data on 1,904 patients undergoing isolated coronary artery bypass grafting (CABG) and stratified them by duration of intubation time after surgery - 0-6, 6-9, 9-12, 12-24 and over 24 hours. Postoperative complications risk analysis was performed using multivariate logistic regression analysis for patients extubated ≤12 and >12 hours.
resultsIntubation percentages in each time cohort were as follows: 0-6 hours - 7.8%, 6-9 hours - 17.3%, 9-12 hours - 26.8%, 12-24 hours - 44.4% and >24 hours - 3.7%. Patients extubated ≤12 hours after CABG were younger, mostly males, more often smokers, with lower preoperative risk. They had lower 30-day mortality (2.02% vs 4.59%,
conclusionResults indicate that risk of postoperative complications does not increase until intubation time exceeds 12 hours. Shorter intubation time is seen in younger, men and smokers. Intubation time >12 hours is a risk factor for postoperative delirium and hemofiltration after cardiac surgery.
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