ArticleNeuropsychiatric disease and treatment2018
Predictors of sleep disturbance in heroin users receiving methadone maintenance therapy: a naturalistic study in Taiwan.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Prevalence of sleep-related symptoms in patients receiving methadone maintenance treatment: a systematic review and meta-analysis.Addiction science & clinical practice · 2026Pooled it
- Sleep Health Among Adults in Outpatient Opioid Use Disorder Treatment: A Systematic Review.Journal of psychosocial nursing and mental health services · 2024Pooled it
- Quality of Sleep and Related Factors in Individuals Undergoing Methadone Maintenance Treatment.Addiction & health · 2025Article
- Gender differences in sleep quality among Iranian traditional and industrial drug users.Neurobiology of sleep and circadian rhythms · 2024Article
- The Impact of Psychological Burdens and Vaccine Worries on Confidence and Adherence to Governmental Policies Against COVID-19 Among Patients with Substance Use Disorder: A Cross-Sectional Study in Taiwan.Neuropsychiatric disease and treatment · 2024Article
- A review of sleep disturbance in adults prescribed medications for opioid use disorder: potential treatment targets for a highly prevalent, chronic problem.Sleep medicine · 2021Review
- Prevalence of Respiratory Disorders during Sleep among Subjects of Methadone Maintenance Therapy Program.Addiction & health · 2021Article
- Factors Associated with Sleep Disorders among Methadone-Maintained Drug Users in Vietnam.International journal of environmental research and public health · 2019Article
- Frequent nightmares in Chinese patients undergoing methadone maintenance therapy: prevalence, correlates, and their association with functional impairment.Neuropsychiatric disease and treatment · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSleep disturbance is a major health concern for heroin users receiving methadone maintenance treatment (MMT). The present study was aimed to investigate the predictors for new-onset clinically predominant sleep disturbance (CPSD) among heroin users receiving MMT.
methodsThis 2-year retrospective study included 152 individuals (127 males and 25 females) with heroin use disorder who visited our MMT clinics for the first time. A univariate Cox proportional hazards regression model (Cox model) was used to estimate the potential factors of subsequent CPSD, followed by a multivariate Cox model to identify significant predictors of CPSD after adjusting for other covariates.
resultsTwenty-nine (19.1%) participants developed CPSD during the 2-year period. After forward selection in the Cox model, earlier age at onset of heroin exposure (OR=0.95;
conclusionWe identified predictors that were significantly associated with new-onset CPSD, and clinicians should be aware of sleep disturbance in heroin users receiving MMT with these risk factors. Future studies are necessary to verify our findings and extend the applicability.
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