Evidence map›Paper›PMID 30464458›Full record

ArticleInternational journal of nanomedicine2018

Synthesis of gold nanoparticles with

Pengfei Zhang, Peicheng Wang, Lei Yan, Lifeng Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Biogenic synthesis of AuNPs usingIndian journal of microbiology · 2023
    Article
  6. In-vitro and ex-vivo antidiabetic, and antioxidant activities of Box-Behnken design optimizedSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Toxicology research · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Synthesis of Biogenic Gold Nanoparticles fromMolecules (Basel, Switzerland) · 2020
    Article
  17. Review
  18. Article
  19. Anti-osteoporotic Effect ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pengfei ZhangDepartment of Otolaryngology - Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China, z8553406@sina.com.
Peicheng WangDepartment of Otolaryngology - Head and Neck Surgery, Weihai Municipal Hospital, Weihai, Shandong 264200, China.
Lei YanInnoscience Research Sdn. Bhd, Subang Jaya, Selangor 47500, Malaysia.
Lifeng LiuDepartment of Otolaryngology - Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China, z8553406@sina.com.
First Affiliated Hospital of Xi'an Jiaotong University · CNWeihai Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNasopharyngeal cancer (NPC) is one of the subtypes of head and neck cancers. It occurs rarely, and its prevalence depends mainly on geographical location. Modern-day research is focused on coupling nanotechnology and traditional medicine for combating cancers. Gold nanoparticles (AuNPs) were synthesized from

methodsCharacterization of the synthesized AuNPs was done by different techniques such as ultraviolet-visible spectrum absorption, X-ray diffraction, dynamic light scattering, Fourier transform infrared spectroscopy, transmission electron microscopy, and energy-dispersive X-ray analysis.

resultsAll the results showed the successful green synthesis of AuNPs from Sx, which induced apoptosis of C666-1 cell line (NPC cell line). There was a decline in both cell viability and colony formation in C666-1 cells upon treatment with Sx-AuNPs. The cell death was proved to be caused by autophagy and mitochondrial-dependent apoptotic pathway.

conclusionThus, due to their anticancer potential, these nanoparticles coupled with Sx can be used for in vivo applications and clinical research in future.

Indexed as

Antineoplastic AgentsApoptosisAutophagyCell Line, TumorCell SurvivalDNA FragmentationDynamic Light ScatteringGoldHumansMetal NanoparticlesMitochondriaNasopharyngeal CarcinomaPlant ExtractsReactive Oxygen SpeciesSolanumSpectrophotometry, UltravioletAntineoplastic AgentsGoldPlant ExtractsReactive Oxygen SpeciesapoptosisC666-1 cellsgold nanoparticleROSSolanum xanthocarpum

Identifiers

PMID30464458
PMCPMC6219121
OpenAlexW2898720622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.