ArticleScientific reports2018
Interplay among steroids, body condition and immunity in response to long-term captivity in toads.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 54 citations in OpenAlex.
- Contrasting effects of transdermal and implant corticosterone treatments in the American bullfrog wound healing.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Testosterone immunomodulation in free-living and captivePhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Introduction to the special issue Amphibian immunity: stress, disease and ecoimmunology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Snap-freezing in the Field: Effect of Sample Holding Time on Performance of Bactericidal Assays.Integrative and comparative biology · 2022Article
- Captivity induces large and population-dependent brain transcriptomic changes in wild-caught cane toads (Rhinella marina).Molecular ecology · 2022Article
- Article
- Metabolic cold adaptation in the Asiatic toad: intraspecific comparison along an altitudinal gradient.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
- Reference Intervals in Combined Veterinary Clinical Examinations of Male Black-Spotted Pond Frogs (Animals : an open access journal from MDPI · 2021Article
- Short-term stressors and corticosterone effects on immunity in male toads (Brain, behavior, & immunity - health · 2021Article
- Validation of stable reference genes in Staphylococcus aureus to study gene expression under photodynamic treatment: a case study of SEB virulence factor analysis.Scientific reports · 2020Article
- Chronic captivity stress in wild animals is highly species-specific.Conservation physiology · 2019Article
- Time-related immunomodulation by stressors and corticosterone transdermal application in toads.PloS one · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Stressful experiences can promote harmful effects on physiology and fitness. However, stress-mediated hormonal and immune changes are complex and may be highly dependent on body condition. Here, we investigated captivity-associated stress effects, over 7, 30, 60, and 90 days on plasma corticosterone (CORT) and testosterone (T) levels, body index, and innate immunity (bacterial killing ability and phagocytosis of peritoneal cells) in toads (Rhinella icterica). Toads in captivity exhibited elevated CORT and decreased T and immunity, without changes in body index. The inter-relationships between these variables were additionally contrasted with those obtained previously for R. schneideri, a related species that exhibited extreme loss of body mass under the same captive conditions. While T and phagocytosis were positively associated in both species, the relationship between CORT and bacterial killing ability was dependent on body index alterations. While CORT and bacterial killing ability were positively associated for toads that maintained body index, CORT was negatively associated with body index in toads that lost body mass over time in captivity. In these same toads, body index was positively associated with bacterial killing ability. These results demonstrate that steroids-immunity inter-relationships arising from prolonged exposure to a stressor in toads are highly dependent on body condition.
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