ArticleThe European respiratory journal2019
Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life.
Article in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04697251 (Application of Forced Oscillation Technique in Infancy), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Forced Oscillation Technique in Infancy
Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Respiratory oscillometry in infants: present challenges and future opportunities.Paediatric respiratory reviews · 2026Review
- Early-life lung function deficits partially explain the link between maternal asthma and bronchiolitis or asthma in offspring.BMJ open respiratory research · 2026Article
- As the twig is bent, so the tree grows: the importance of early life influences on lung growth and respiratory health.Translational pediatrics · 2026Article
- The effect of moderate-to-late preterm birth on lung function over the first 5 years of life in a South African birth cohort.ERJ open research · 2025Article
- Intra-breath respiratory mechanics of prematurity-associated lung disease phenotypes in school-aged children.ERJ open research · 2025Article
- Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort.The Lancet. Child & adolescent health · 2024Article
- Intra-breath changes in respiratory mechanics are sensitive to history of respiratory illness in preschool children: the SEPAGES cohort.Respiratory research · 2024Article
- Oscillatory mechanics trajectory in very preterm infants: a cohort study.Pediatric research · 2023Observational
- The impact of antenatal and postnatal indoor air pollution or tobacco smoke exposure on lung function at 3 years in an African birth cohort.Respirology (Carlton, Vic.) · 2023Article
- Oscillometry and spirometry are not interchangeable when assessing the bronchodilator response in children and young adults born preterm.Pediatric pulmonology · 2023Article
- Normal values of respiratory oscillometry in South African children and adolescents.ERJ open research · 2023Article
- Early childhood wheezing phenotypes and determinants in a South African birth cohort: longitudinal analysis of the Drakenstein Child Health Study.The Lancet. Child & adolescent health · 2023Article
- Understanding the fundamentals of oscillometry from a strip of lung tissue.Frontiers in physiology · 2022Review
- Characterization of chronic lung allograft dysfunction phenotypes using spectral and intrabreath oscillometry.Frontiers in physiology · 2022Article
- Lung Function in Preschool Children in Low and Middle Income Countries: An Under-Represented Potential Tool to Strengthen Child Health.Frontiers in pediatrics · 2022Review
- Respiratory Oscillometry in Newborn Infants: Conventional and Intra-Breath Approaches.Frontiers in pediatrics · 2022Article
- Intra-breath oscillometry for the evaluation of lung function in children and adolescents with a history of preterm birth.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Oscillometry of the respiratory system: a translational opportunity not to be missed.American journal of physiology. Lung cellular and molecular physiology · 2021Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
Lower respiratory tract illness (LRTI) is a leading cause of mortality and morbidity in children. Sensitive and noninvasive infant lung function techniques are needed to measure risk for and impact of LRTI on lung health. The objective of this study was to investigate whether lung function derived from the intra-breath forced oscillation technique (FOT) was able to identify healthy infants at risk of LRTI in the first year of life.Lung function was measured with the novel intra-breath FOT, in 6-week-old infants in a South African birth cohort (Drakenstein Child Health Study). LRTI during the first year was confirmed by study staff. The association between baseline lung function and LRTI was assessed with logistic regression and odds ratios determined using optimal cut-off values.Of the 627 healthy infants with successful lung function testing, 161 (24%) had 238 LRTI episodes subsequently during the first year. Volume dependence of respiratory resistance (Δ
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.