Evidence map›Paper›PMID 30463882›Full record

ArticleG3 (Bethesda, Md.)2019

Perturbations of Transcription and Gene Expression-Associated Processes Alter Distribution of Cell Size Values in

Nairita Maitra, Jayamani Anandhakumar, Heidi M Blank, Craig D Kaplan, Michael Polymenis

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nairita MaitraDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Jayamani AnandhakumarDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Heidi M BlankDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-2251-5246
Craig D KaplanDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843 craig.kaplan@pitt.edu polymenis@tamu.edu.ORCID 0000-0002-7518-695X
Michael PolymenisDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843 craig.kaplan@pitt.edu polymenis@tamu.edu.ORCID 0000-0003-1507-0936
Texas A&M University · US

Funding

Mechanism and Regulation of RNA Polymerase II ElongationR01GM097260 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, CRAIG · 2011 to 2020
$3.3M
Coupling Of Protein Synthesis With Cell DivisionR01GM123139 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI POLYMENIS, MICHAEL S · 2017 to 2024
$2.9M
NIGMS NIH HHS R01 GM097260NIGMS NIH HHS R01 GM123139
6 · The paper itself

Abstract

The question of what determines whether cells are big or small has been the focus of many studies because it is thought that such determinants underpin the coupling of cell growth with cell division. In contrast, what determines the overall pattern of how cell size is distributed within a population of wild type or mutant cells has received little attention. Knowing how cell size varies around a characteristic pattern could shed light on the processes that generate such a pattern and provide a criterion to identify its genetic basis. Here, we show that cell size values of wild type

Indexed as

Transcription, GeneticCell SizeDNA-Directed RNA PolymerasesGene DeletionGene Expression Regulation, FungalGenetics, PopulationRNA Polymerase IISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsDNA-Directed RNA PolymerasesRNA Polymerase IIRPB1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factorscell sizegamma distributionRNA polymeraseRSCTHO

Identifiers

PMID30463882
PMCPMC6325893
OpenAlexW2899192870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.