Evidence map›Paper›PMID 30463621›Full record

ArticleCardiovascular diabetology2018

Unrecognised cardiovascular disease in type 2 diabetes: is it time to act earlier?

Guntram Schernthaner, Chaim Lotan, Elina Baltadzhieva-Trendafilova, Jonas Ceponis, Martin Clodi, Kristine Ducena, Eva Goncalvesova, Cristian Guja, Marek Honka, Andrej Janež and 7 more

Abstract read
In one paragraph

Article in Cardiovascular diabetology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Guntram SchernthanerMedical University of Vienna, Vienna, Austria. guntram.schernthaner@meduniwien.ac.at.
Chaim LotanHadassah-Hebrew University Medical Center, Jerusalem, Israel. chaim.lotan@gmail.com.
Elina Baltadzhieva-TrendafilovaNational Cardiology Hospital, Sofia, Bulgaria.
Jonas CeponisInstitute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Martin ClodiDepartment of Internal Medicine, St. John Hospital, Linz, Austria.
Kristine DucenaFaculty of Internal Medicine, University of Latvia, Riga, Latvia.
Eva GoncalvesovaDepartment of Heart Failure and Transplantation, National Institute of Cardiovascular Diseases, Bratislava, Slovak Republic.
Cristian GujaDepartment of Diabetes, Nutrition and Metabolic Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Marek HonkaFakultní Nemocnice Ostrava, Poruba, Czech Republic.
Andrej JanežNational Institute of Endocrinology and Diabetology, Lubochna, Slovakia.
Nebojša LalićClinic for Endocrinology, Diabetes and Metabolic Diseases, CCS, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Roger LehmannDivision of Endocrinology and Diabetes of the University Hospital, Zurich, Switzerland.
Noémi NyolczasDepartment of Cardiology, Hungarian Defence Forces-Medical Centre, Budapest, Hungary.
Priit PauklinDepartment of Cardiology, Tartu University Hospital, Tartu, Estonia.
Andrzej RynkiewiczDepartment of Cardiology and Cardiosurgery, School of Medicine, University of Warmia and Mazury, Olsztyn, Poland.
Igor SergienkoRussian Cardiology Research Complex, Moscow, Russia.
Lea Smirčić DuvnjakDepartment of Endocrinology and Metabolic Diseases, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, School of Medicine, Endocrinology and Metabolic Diseases, University of Zagreb, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the most significant prognostic factor in individuals with type 2 diabetes (T2D). However, a significant number of individuals may develop CVD that does not present with the classic angina-related or heart failure symptoms. In these cases, CVD may seem to be 'silent' or 'asymptomatic', but may be more accurately characterised as unrecognised diabetic cardiac impairment. An initial step to raise awareness of unrecognised CVD in individuals with T2D would be to reach a consensus regarding the terminology used to describe this phenomenon. By standardising the terminologies, and agreeing on the implementation of an efficient screening program, it is anticipated that patients will receive an earlier diagnosis and appropriate and timely treatment. Given the availability of anti-diabetic medications that have been shown to concomitantly reduce CV risk and mortality, it is imperative to improve early identification and initiate treatment as soon as possible in order to enable as many patients with T2D as possible to benefit.

Indexed as

Asymptomatic DiseasesBiomarkersBlood GlucoseCardiovascular DiseasesDiabetes Mellitus, Type 2Early DiagnosisHumansHypoglycemic AgentsMass ScreeningPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsBiomarkersBlood GlucoseHypoglycemic AgentsAsymptomaticAtypicalCardiovascular diseaseScreeningSilentType 2 diabetesUnrecognised

Identifiers

PMID30463621
PMCPMC6247507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.