ArticleHealth and quality of life outcomes2018
Can acute clinical outcomes predict health-related quality of life after stroke: a one-year prospective study of stroke survivors.
Article in Health and quality of life outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health State Utility Values in People With Stroke: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2022Pooled it
- Influence of stroke infarct location on quality of life assessed in a multivariate lesion-symptom mapping study.Scientific reports · 2021Trial
- Longitudinal changes in health-related quality of life in working-age adults one year after ischaemic stroke: findings from the FRAILTY study.Central European journal of public health · 2026Article
- Utility-weighted modified rankin scale scores in patients with ischemic stroke: a multicenter observational study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Observational
- Poor Sleep Health Early After Stroke is Associated with Lower Quality of Life Later After Stroke.medRxiv : the preprint server for health sciences · 2025Article
- The Role of Atrial Fibrillation and Oral Anticoagulation Status in Health-Related Quality of Life 12 Months After Ischemic Stroke or TIA.Brain and behavior · 2025Article
- Gait speed at the acute phase predicted health-related quality of life at 3 and 12 months after stroke: a prospective cohort study.Journal of rehabilitation medicine · 2024Article
- Health-related quality of life in post-stroke patients attended at tertiary-level hospitals in Bangladesh.Frontiers in stroke · 2024Article
- Individuals with stroke three months after hospital discharge reported worse quality of life during the COVID-19 pandemic.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023Article
- Factors affecting the quality of life after ischemic stroke in young adults: a scoping review.Health and quality of life outcomes · 2023Article
- Health-related quality of life profiles and their dimension-specific associated factors among Malaysian stroke survivors: a cross sectional study.Health and quality of life outcomes · 2021Article
- Profiles of patients' self-reported health after acute stroke.Neurological research and practice · 2021Article
- Factors Affecting Quality of Life among Post-Stroke Patients in the Sub-Himalayan Region.Journal of neurosciences in rural practice · 2020Article
Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
backgroundHealth-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients' perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate the extent to which clinical outcomes during admission predict HRQoL at 3 months and 1 year post-stroke.
methodsStroke patients admitted to five tertiary hospitals in Singapore were assessed with Shah-modified Barthel Index (Shah-mBI), National Institute of Health Stroke Scale (NIHSS), Modified Rankin Scale (mRS), Mini-Mental State Examination (MMSE), and Frontal Assessment Battery (FAB) before discharge, and the EQ-5D questionnaire at 3 months and 12 months post-stroke. Association of clinical measures with the EQ index at both time points was examined using multiple linear regression models. Forward stepwise selection was applied and consistently significant clinical measures were analyzed for their association with individual dimensions of EQ-5D in multiple logistic regressions.
resultsAll five clinical measures at baseline were significant predictors of the EQ index at 3 months and 12 months, except that MMSE was not significantly associated with the EQ index at 12 months. NIHSS (3-month standardized β = - 0.111; 12-month standardized β = - 0.109) and mRS (3-month standardized β = - 0.122; 12-month standardized β = - 0.080) were shown to have a larger effect size than other measures. The contribution of NIHSS and mRS as significant predictors of HRQoL was mostly explained by their association with the mobility, self-care, and usual activities dimensions of EQ-5D.
conclusionsHRQoL at 3 months and 12 months post-stroke can be predicted by clinical outcomes in the acute phase. NIHSS and mRS are better predictors than BI, MMSE, and FAB.
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