Evidence map›Paper›PMID 30463384›Full record

ArticleMolecules (Basel, Switzerland)2018

Preparation of Enantiomeric β-(2',5'-Dimethylphenyl)Bromolactones, Their Antiproliferative Activity and Effect on Biological Membranes.

Witold Gładkowski, Aleksandra Włoch, Aleksandra Pawlak, Angelika Sysak, Agata Białońska, Marcelina Mazur, Paweł Mituła, Gabriela Maciejewska, Bożena Obmińska-Mrukowicz, Halina Kleszczyńska

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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  10. NewMolecules (Basel, Switzerland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Witold GładkowskiDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. witold.gladkowski@upwr.edu.pl.ORCID 0000-0002-3271-779X
Aleksandra WłochDepartment of Physics and Biophysics, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. aleksandra.wloch@upwr.edu.pl.
Aleksandra PawlakDepartment of Pharmacology and Toxicology, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland. aleksandra.pawlak@upwr.edu.pl.
Angelika SysakDepartment of Pharmacology and Toxicology, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland. angelika.sysak@upwr.edu.pl.
Agata BiałońskaDepartment of Crystallography, University of Wrocław, Joliot Curie 14, 50-383 Wrocław, Poland. agata.bialonska@uwr.edu.pl.
Marcelina MazurDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. marcelina.mazur@upwr.edu.pl.ORCID 0000-0002-6192-5248
Paweł MitułaInstitute of Environmental Engineering, Wroclaw University of Environmental and Life Sciences, Grunwaldzki Sq 24, 50-363 Wrocław, Poland. pawel.mitula@upwr.edu.pl.
Gabriela MaciejewskaCentral Laboratory of the Instrumental Analysis, Wroclaw University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland. gabriela.maciejewska@pwr.edu.pl.
Bożena Obmińska-MrukowiczDepartment of Pharmacology and Toxicology, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland. bozena.obminska-mrukowicz@upwr.edu.pl.
Halina KleszczyńskaDepartment of Physics and Biophysics, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. halina.kleszczynska@upwr.edu.pl.
Wrocław University of Environmental and Life Sciences · PLUniversity of Wrocław · PLWrocław University of Science and Technology · PL

Funding

Wroclaw Centre of Biotechnology, programme The Leading National Research Centre (KNOW) 2014-2018
6 · The paper itself

Abstract

Three novel enantiomeric pairs of bromolactones possesing a 2,5-dimethylphenyl substituent at the β-position of the lactone ring have been synthesized from corresponding enantiomeric (

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell MembraneCell ProliferationDogsHumansJurkat CellsKineticsLactonesMolecular StructureStereoisomerismAntineoplastic AgentsLactonesabsolute configurationsantiproliferative activitybiological membranesbromolactonizationerythrocyteshemolytic activitylactones

Identifiers

PMID30463384
PMCPMC6278266
OpenAlexW2900715605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.