Evidence map›Paper›PMID 30463299›Full record

ArticleInternational journal of molecular sciences2018

Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and

Minh Tu Nguyen, Milán Somogyvári, Csaba Sőti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Antiaging Effect of 2-Foods (Basel, Switzerland) · 2025
    Article
  2. Article
  3. MACSPI enables tissue-selective proteomic and interactomic analyses in multicellular organisms.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Organismal Roles of Hsp90.Biomolecules · 2023
    Review
  5. Article
  6. Review
  7. Enhanced Healthspan inFrontiers in pharmacology · 2021
    Article
  8. Article
  9. Healthspan Enhancement by Olive Polyphenols inInternational journal of molecular sciences · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Minh Tu NguyenDepartment of Medical Chemistry, Semmelweis University, H-1094 Budapest, Hungary. minhtu.nguyen@med.semmelweis-univ.hu.
Milán SomogyváriDepartment of Medical Chemistry, Semmelweis University, H-1094 Budapest, Hungary. somogyvari.milan@med.semmelweis-univ.hu.
Csaba SőtiDepartment of Medical Chemistry, Semmelweis University, H-1094 Budapest, Hungary. soti.csaba@med.semmelweis-univ.hu.ORCID 0000-0002-4057-7678
Semmelweis University · HU

Funding

Hungarian Science Foundation OTKA K 116525Semmelweis Egyetem Merit Prize
6 · The paper itself

Abstract

Sirtuin 1 (SIRT1) othologs are ubiquitous NAD⁺-dependent deacetylases that act as nutrient sensors and modulate metabolism and stress responses in diverse organisms. Both mammalian SIRT1 and

Indexed as

AnimalsBenzoquinonesCaenorhabditis elegansChlorocebus aethiopsCOS CellsHep G2 CellsHSP90 Heat-Shock ProteinsHumansLactams, MacrocyclicMammalsModels, BiologicalProteasome Endopeptidase ComplexProtein BindingProtein StabilityProteolysisSirtuin 1BenzoquinonesgeldanamycinHSP90 Heat-Shock ProteinsLactams, MacrocyclicProteasome Endopeptidase ComplexSirtuin 1agingdaf-21epigeneticsHDACmetabolismproteostasissignalingsir-2.1stress

Identifiers

PMID30463299
PMCPMC6274930
OpenAlexW2901020956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.