ArticleAnimals : an open access journal from MDPI2018
Hypoxia and Oxidative Stress Are Associated with Reduced Fetal Growth in Twin and Undernourished Sheep Pregnancies.
Article in Animals : an open access journal from MDPI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Fetal programming in sheep: effects on pre- and postnatal development in lambs.Journal of animal science · 2020Pooled it
- Effects of Prenatal Ursodeoxycholic Acid and Probiotic Supplementation on Stress Parameters, Immune Response and Lamb Survival Rates in Ewes.Veterinary medicine and science · 2026Article
- Rumen epithelial functional adaptation in alpine ewes: transcriptomic effects of micronutrient premix and concentrate supplementation levels.Stress biology · 2026Article
- Doppler Ultrasound Indices and Fetal Biometry as Prenatal Markers of SGA or Non-SGA Developmental Trajectories in Naturally Nutrient-Restricted Sheep Pregnancies from Patagonia.Animals : an open access journal from MDPI · 2026Article
- Supplementation with Polyphenols (Olive and Grape Extracts) Improves Pregnancy Outcomes in Underfed Sheep.Antioxidants (Basel, Switzerland) · 2025Article
- Effect of N-Carbamylglutamate Supplementation in Late Pregnancy on Nutrient-Restricted Twin-Bearing Ewes on the Pre-Lambing Maternal Metabolome, Colostrum Quality and Lamb Birth Weight.Animals : an open access journal from MDPI · 2025Article
- Genomic Adaptation, Environmental Challenges, and Sustainable Yak Husbandry in High-Altitude Pastoral Systems.Veterinary sciences · 2025Review
- Acremonium terricola culture supplementation in the diet of pregnant and lactating Ewes can improve the production performance of Ewes and lambs by regulating maternal metabolism and antibody delivery.BMC veterinary research · 2025Article
- Increasing the Understanding of Nutrient Transport Capacity of the Ovine Placentome.Animals : an open access journal from MDPI · 2024Article
- Chronic Undernutrition in Ovine Twin Pregnancies Abolishes Differences in Birth Weight Due to Sex: An Evaluation of the Role of Nutritional and Antioxidant Supplementation.Animals : an open access journal from MDPI · 2024Article
- The Effect of N-Carbamylglutamate Supplementation during the Last Third of Gestation on the Growth and Development of Fetuses Born to Nutrient-Restricted Twin-Bearing Ewes.Animals : an open access journal from MDPI · 2024Article
- Colostrum traits and newborn body weight and growth: comparison between single and twin underfed sheep pregnancies.Frontiers in veterinary science · 2023Article
- Oxidative Stress and Fetal Growth Restriction Set Up Earlier in Undernourished Sheep Twin Pregnancies: Prevention with Antioxidant and Nutritional Supplementation.Antioxidants (Basel, Switzerland) · 2022Article
- Changes in Digestive Microbiota, Rumen Fermentations and Oxidative Stress around Parturition Are Alleviated by Live Yeast Feed Supplementation to Gestating Ewes.Journal of fungi (Basel, Switzerland) · 2021Article
- Maternal Supplementation with Herbal Antioxidants during Pregnancy in Swine.Antioxidants (Basel, Switzerland) · 2021Article
- Neonatal hair profiling reveals a metabolic phenotype of monochorionic twins with selective intrauterine growth restriction and abnormal umbilical artery flow.Molecular medicine (Cambridge, Mass.) · 2020Article
- Supplementation of Underfed Twin-Bearing Ewes with Herbal Vitamins C and E: Impacts on Birth Weight, Postnatal Growth, and Pre-Weaning Survival of the Lambs.Animals : an open access journal from MDPI · 2020Article
- Article
- Maternal Supplementation with Antioxidant Vitamins in Sheep Results in Increased Transfer to the Fetus and Improvement of Fetal Antioxidant Status and Development.Antioxidants (Basel, Switzerland) · 2019Article
- Evaluating Amino Acid Profiles and Blood Gas Concentrations Between Single and Twin Merino Newborn Lambs.Animal science journal = Nihon chikusan GakkaihoArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Low birth weight has profound implications for perinatal mortality and morbidity in lambs, causing higher mortality and lower growth potential. Low birth weight, as a consequence of fetal growth restriction, occurs in undernourished and multiple pregnancies, where hypoxia and oxidative stress could play a critical role. Our aim was to establish the effects of nutritional deprivation and pregnancy rank on fetal growth, oxygenation, and oxidative status in sheep pregnancies under extensive Patagonian conditions. At 30 days after mating, single- and twin-bearing ewes were offered only natural pasture (undernutrition group) or natural pasture plus concentrate supplementation (well-nourished group). At day 140 of gestation, blood gases and redox status were evaluated in venous cord blood, and fetal biometric characteristics were obtained after cesarean section. Both maternal undernutrition and twinning led to decreased oxygen supply to the fetuses (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.