Evidence map›Paper›PMID 30462879›Full record

ArticleAngewandte Chemie (International ed. in English)2019

Aliphatic Radical Relay Heck Reaction at Unactivated C(sp

Padon Chuentragool, Dongari Yadagiri, Taiki Morita, Sumon Sarkar, Marvin Parasram, Yang Wang, Vladimir Gevorgyan

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Site-Selective C─H Bond Functionalization of Sugars.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. Article
  7. Illuminating Palladium Catalysis.Accounts of chemical research · 2025
    Article
  8. Article
  9. Article
  10. Recent Advances in Visible Light Induced Palladium Catalysis.Angewandte Chemie (International ed. in English) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Palladium Hydride-Enabled Hydroalkenylation of Strained Molecules.Journal of the American Chemical Society · 2022
    Article
  16. Article
  17. Article
  18. Photo-Induced Ruthenium-Catalyzed Double Remote C(spAngewandte Chemie (International ed. in English) · 2022
    Article
  19. C2-ketonylation of carbohydratesChemical science · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Padon ChuentragoolDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Dongari YadagiriDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Taiki MoritaDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Sumon SarkarDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Marvin ParasramDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Yang WangDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.
Vladimir GevorgyanDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Rm. 4500, Chicago, IL, 60607, USA.ORCID 0000-0002-7836-7596

Funding

Transition Metal-Radical Hybrid Methods for Organic SynthesisR01GM120281 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI GEVORGYAN, VLADIMIR · 2017 to 2024
$2.5M
Division of Chemistry CHE-1663779NIGMS NIH HHS R01 GM120281
6 · The paper itself

Abstract

The Mizoroki-Heck reaction is one of the most efficient methods for alkenylation of aryl, vinyl, and alkyl halides. Given its innate nature, this protocol requires the employment of compounds possessing a halogen atom at the site of functionalization. However, the accessibility of organic molecules possessing a halogen atom at a particular site in aliphatic systems is extremely limited. Thus, a protocol that allows a Heck reaction to occur at a specific nonfunctionalized C(sp

Indexed as

AlcoholsFree RadicalsMolecular StructureAlcoholsFree RadicalsC−H activationHeck reactionpalladiumphotochemistryradicals

Identifiers

PMID30462879
PMCPMC6359925

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.