Trial reportAlcoholism, clinical and experimental research2019
Working Memory Training in Alcohol Use Disorder: A Randomized Controlled Trial.
Trial report in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05879198 (Train Your Brain), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Train Your Brain: A Pilot Project to Improve Memory and Decision Making to Improve Outcomes Among Youth
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Cognitive Training Effectiveness on Memory, Executive Functioning, and Processing Speed in Individuals With Substance Use Disorders: A Systematic Review.Frontiers in psychology · 2021Pooled it
- A Personalized and Smartphone-Based Serious Gaming App Targeting Cognitive Impairments in Alcohol Use Disorder: Double-Blinded, Randomized Controlled Efficacy Trial Among Outpatients.JMIR mental health · 2025Trial
- Adaptive working memory training does not produce transfer effects in cognition and neuroimaging.Translational psychiatry · 2022Trial
- Working Memory Training Reduces Cigarette Smoking Among Low-Income Individuals With Elevated Delay Discounting.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Trial
- Cognitive training in recently-abstinent individuals with alcohol use disorder improves emotional stroop performance: Evidence from a randomized pilot trial.Drug and alcohol dependence · 2022Trial
- Combining approach bias modification with working memory training during inpatient alcohol withdrawal: an open-label pilot trial of feasibility and acceptability.Substance abuse treatment, prevention, and policy · 2019Trial
- Prefrontal TDCS does not improve working memory performance in individuals with chronic alcohol and tobacco use.IBRO neuroscience reports · 2026Article
- The Effectiveness of Cognitive Rehabilitation on Cognitive Flexibility, Working Memory, Response Inhibition, and Drug Craving in Abstinent Addicts.Addiction & health · 2026Article
- Adolescent executive function as a resilience factor in the family stress model among Mexican-origin families.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2025Article
- The impact of memory training on abstinence among individuals with alcohol use disorder.Frontiers in psychiatry · 2025Article
- Approach-Bias Retraining and Other Training Interventions as Add-On in the Treatment of AUD Patients.Current topics in behavioral neurosciences · 2025Review
- Effectiveness of a virtual reality-based cognitive training program on memory, executive functioning, and processing speed in individuals with substance use disorders: a quasi-experimental study.Frontiers in behavioral neuroscience · 2025Article
- Severe alcohol use and COVID-19: implications for physical and mental health.Frontiers in psychiatry · 2025Review
- The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial.Contemporary clinical trials · 2024Article
- Prenatal ethanol and cannabis exposure have sex- and region-specific effects on somatostatin and neuropeptide Y interneurons in the rat hippocampus.Alcohol, clinical & experimental research · 2024Article
- Ethanol's impact on the brain: a neurobiological perspective on the mechanisms of memory impairment.Molecular biology reports · 2024Review
- The Functional-Cognitive and Sensory Treatment (F-CaST) to improve rehabilitation outcomes of individuals with substance use disorder: a study protocol for a mixed-method randomized controlled trial.Addiction science & clinical practice · 2024Article
- Cognitive training interventions for substance use disorders: what they really offer?Frontiers in public health · 2024Article
- Age-related cognitive decline is accelerated in alcohol use disorder.Neuropsychopharmacology reports · 2023Article
- Pharmacological Treatment of Alcohol Cravings.Brain sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAlcohol use disorder (AUD) is associated with cognitive deficits such as impaired executive functions, which are hypothesized to contribute to the progression of the disease and worsen treatment outcome. Training of working memory (WM) to improve cognitive functions and thereby reduce alcohol use has been proposed as a novel treatment strategy.
methodsPatients with AUD (n = 50) who were recruited to an outpatient addiction clinic were randomized to receive 5 weeks of active WM training or control training. Participants had weekly follow-up visits, and all cognitive training sessions were done online at home. Primary outcomes were WM function and change in self-reported heavy drinking. Secondary outcomes were craving, other drinking outcomes, and performance on a range of neuropsychological tasks from the Cambridge Neuropsychological Test Automated Battery.
resultsThe active training group demonstrated a significantly greater improvement in verbal WM compared with the control group. No statistically significant effect of training was found on the primary drinking outcome, but a trend was observed indicating that WM training reduces the number of drinks per drinking occasion. WM training had no statistically significant effect on any of the other neuropsychological tasks.
conclusionsCognitive training can improve WM function in individuals with AUD, suggesting that such interventions are feasible to administer in this patient population. The results do not support an effect of WM training on heavy drinking or transfer effects to other cognitive domains. Future studies should evaluate WM training as an adjunct to evidence-based treatments for AUD to assess potential synergistic effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.