Trial reportPloS one2018
Cortical control of a tablet computer by people with paralysis.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00912041 (BrainGate2), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evolution of brain-computer interface technologies for stroke rehabilitation: a bibliometric integration of neural decoding and functional recovery (2016-2025).Frontiers in neuroscience · 2026Pooled it
- Speech motor cortex enables BCI cursor control and click.Journal of neural engineering · 2025Trial
- How different immersive environments affect intracortical brain computer interfaces.Journal of neural engineering · 2025Trial
- Speech-related dorsal motor cortex activity does not interfere with iBCI cursor control.Journal of neural engineering · 2020Trial
- Gesture encoding in human left precentral gyrus neuronal ensembles.Communications biology · 2025Article
- Article
- Invasive Brain-Computer Interface for Communication: A Scoping Review.Brain sciences · 2025Review
- qPRF: A system to accelerate population receptive field modeling.NeuroImage · 2025Article
- A high-performance brain-computer interface for finger decoding and quadcopter game control in an individual with paralysis.Nature medicine · 2025Article
- To move without moving: a perspective article on motor imagery.Frontiers in psychology · 2025Article
- Making Video Games More Inclusive for People Living With Motor Neuron Disease: Scoping Review.JMIR rehabilitation and assistive technologies · 2024Article
- Speech motor cortex enables BCI cursor control and click.bioRxiv : the preprint server for biology · 2024Article
- Reducing power requirements for high-accuracy decoding in iBCIs.Journal of neural engineering · 2024Article
- Implanted cortical neuroprosthetics for speech and movement restoration.Journal of neurology · 2024Review
- A click-based electrocorticographic brain-computer interface enables long-term high-performance switch scan spelling.Communications medicine · 2024Article
- Measuring instability in chronic human intracortical neural recordings towards stable, long-term brain-computer interfaces.Communications biology · 2024Article
- Decoding Single and Paired Phonemes Using 7T Functional MRI.Brain topography · 2024Article
- How different immersive environments affect intracortical brain computer interfaces.bioRxiv : the preprint server for biology · 2024Article
- A flexible intracortical brain-computer interface for typing using finger movements.bioRxiv : the preprint server for biology · 2024Article
- Brain control of bimanual movement enabled by recurrent neural networks.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software and personalized input devices can improve access, but often provide only limited functionality. In this study, three research participants with tetraplegia who had multielectrode arrays implanted in motor cortex as part of the BrainGate2 clinical trial used an intracortical brain-computer interface (iBCI) to control an unmodified commercial tablet computer. Neural activity was decoded in real time as a point-and-click wireless Bluetooth mouse, allowing participants to use common and recreational applications (web browsing, email, chatting, playing music on a piano application, sending text messages, etc.). Two of the participants also used the iBCI to "chat" with each other in real time. This study demonstrates, for the first time, high-performance iBCI control of an unmodified, commercially available, general-purpose mobile computing device by people with tetraplegia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.