Evidence map›Paper›PMID 30462500›Full record

ArticleJournal of the American Chemical Society2019

Structures and Reactivities of Sodiated Evans Enolates: Role of Solvation and Mixed Aggregation on the Stereochemistry and Mechanism of Alkylations.

Zirong Zhang, David B Collum

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Cyclic Imine-BFSynlett : accounts and rapid communications in synthetic organic chemistry · 2025
    Article
  2. Copper(I)-Catalyzed Enantioselective α-Alkylation of 2-Acylimidazoles.Journal of the American Chemical Society · 2024
    Article
  3. Photocatalytic Decarboxylative Alkylation of Cyclic Imine-BFJournal of the American Chemical Society · 2024
    Article
  4. Alicyclic-Amine-Derived Imine-BFAngewandte Chemie (International ed. in English) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Structural Motifs of Alkali Metal Superbases in Non-coordinating Solvents.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  12. Article
  13. Wittig Rearrangements of Boron-Based Oxazolidinone Enolates.The Journal of organic chemistry · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zirong ZhangDepartment of Chemistry and Chemical Biology Baker Laboratory , Cornell University , Ithaca , New York 14853-1301 , United States.ORCID 0000-0002-6720-4644
David B CollumDepartment of Chemistry and Chemical Biology Baker Laboratory , Cornell University , Ithaca , New York 14853-1301 , United States.ORCID 0000-0001-6065-1655

Funding

Chemistry of Lithium EnolatesR01GM077167 · NIGMS · CORNELL UNIVERSITY · PI COLLUM, DAVID B. · 2006 to 2018
$4.1M
Alkali Metal Chemistry-Structures, Mechanisms, and ApplicationsR35GM131713 · NIGMS · CORNELL UNIVERSITY · PI COLLUM, DAVID B. · 2019 to 2023
$2.8M
NIGMS NIH HHS R01 GM077167NIGMS NIH HHS R35 GM131713
6 · The paper itself

Abstract

Oxazolidinone-based sodiated enolates (Evans enolates) were generated using sodium diisopropylamide (NaDA) or sodium hexamethyldisilazide (NaHMDS) in the presence of N,N,N',N'-tetramethylethylenediamine (TMEDA), ( R,R)- trans- N,N,N',N'-tetramethylcyclohexanediamine [( R,R)-TMCDA], or ( S,S)-TMCDA.

Indexed as

AlkenesAlkylationKineticsModels, MolecularMolecular ConformationOxazolesSolventsStereoisomerismAlkenesOxazolesoxazolidineSolvents

Identifiers

PMID30462500
PMCPMC7185956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.