ArticleMolecular ecology2019
Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data.
Article in Molecular ecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
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Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Fault-tolerant pedigree reconstruction from pairwise kinship relations.Bioinformatics (Oxford, England) · 2026Article
- The genomic impact of population connectivity and decline in Africa's elephants.Nature communications · 2026Article
- Mitochondrial structure despite nuclear panmixia: sex-specific dispersal dictates population structure in sperm whales.Heredity · 2026Article
- A large mass grave from the Early Iron Age indicates selective violence towards women and children in the Carpathian Basin.Nature human behaviour · 2026Article
- First evidence of polyandry for amazonian stingray (Potamotrygon wallacei Carvalho, Rosa & Araújo 2016) based on genome-wide SNP data.Molecular biology reports · 2026Article
- Evaluating the performance of ancient DNA genetic relatedness estimation methods using high-fidelity pedigree simulations.Genome biology · 2026Article
- Population structure and domestication history of the Javan banteng.Current biology : CB · 2026Article
- Genomic approaches to build de novo elite breeding gene pools from locally adapted landraces.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
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- The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression.Nature communications · 2025Article
- 1206 genomes reveal origin and movement ofScience (New York, N.Y.) · 2025Article
- Ancient genomes provide evidence of demographic shift to Slavic-associated groups in Moravia.Genome biology · 2025Article
- Urban Life Shapes Genetic Diversity in the Green Anole, Anolis carolinensis.Molecular ecology · 2025Article
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- vcfgl: a flexible genotype likelihood simulator for VCF/BCF files.Bioinformatics (Oxford, England) · 2025Article
- PopGLen-a Snakemake pipeline for performing population genomic analyses using genotype likelihood-based methods.Bioinformatics (Oxford, England) · 2025Article
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3 authors.
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Abstract
Knowledge of how individuals are related is important in many areas of research, and numerous methods for inferring pairwise relatedness from genetic data have been developed. However, the majority of these methods were not developed for situations where data are limited. Specifically, most methods rely on the availability of population allele frequencies, the relative genomic position of variants and accurate genotype data. But in studies of non-model organisms or ancient samples, such data are not always available. Motivated by this, we present a new method for pairwise relatedness inference, which requires neither allele frequency information nor information on genomic position. Furthermore, it can be applied not only to accurate genotype data but also to low-depth sequencing data from which genotypes cannot be accurately called. We evaluate it using data from a range of human populations and show that it can be used to infer close familial relationships with a similar accuracy as a widely used method that relies on population allele frequencies. Additionally, we show that our method is robust to SNP ascertainment and applicable to low-depth sequencing data generated using different strategies, including resequencing and RADseq, which is important for application to a diverse range of populations and species.
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