Evidence map›Paper›PMID 30461647›Full record

Observational studyMedicine2018

Effect of community-based extension clinics of methadone maintenance therapy for opiate-dependent clients: A prospective cohort study in Dehong Prefecture, Yunnan Province of China.

Guang Zhang, Yuecheng Yang, Runhua Ye, Dapeng Zhang, Duo Shan, Yifei Hu, Bing Dai, Zhongfu Liu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Guang ZhangNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Yuecheng YangDehong Prefectural Center for Disease Control and Prevention, Mangshi, Yunnan Province.
Runhua YeDehong Prefectural Center for Disease Control and Prevention, Mangshi, Yunnan Province.
Dapeng ZhangNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Duo ShanNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Yifei HuDepartment of Child, Adolescent and Maternal Health, School of Public Health, Capital Medical University, Beijing.
Bing DaiPingdu County Center for Disease Control and Prevention, Pingdu, Shandong Province, China.
Zhongfu LiuNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Center for Disease Control · TWYunnan Center for Disease Control And Prevention · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methadone maintenance therapy (MMT) is effective in treatment of opiate dependents. However, there is a gap between the coverage of standard MMT clinics and the need of opiate dependents. Establishment of extension clinics of methadone maintenance therapy (EMMT) will increase the coverage and improve MMT accessibility. We implemented a prospective cohort study to understand the effects of establishment of community-based EMMT clinics comparing with MMT clinics in Yunnan Province.A total of 462 opiate-dependent clients were interviewed from the community-based EMMT clinics and standard MMT clinics located in 5 counties of Mangshi, Ruili, Longchuan, Yingjiang, and Lianghe in Yunnan Province. The information on the demographic characteristics, drug risk behaviors, quality of life (QOL), and urine testing results for morphine of the clients was collected and compared between the EMMT and MMT clinics. A survival analysis method was utilized to know the retention situation of the newly enrolled clients with Kaplan-Meier method during 9 months treatment.Among the EMMT clients, 96.9% were male; 31.4% were Han; 61.4% were married; 39.0% had primary school education; 95.5% lived with their family or relatives; 96.9% who arrived the clinic less than 15 min; 52.9% had used drugs for more than 10 years; and 16.7% injected drug. After 9 months therapy, there was no difference in the changes of life quality such as physical and psychological features, social relationships, environmental function, and total QOL and well-being between those of EMMT and MMT clinics. The positive detection rate of urine-morphine testing among newly enrolled clients of EMMT clinics decreased as the period of treatment lengthened. The average time of retention for newly enrolled EMMT clients who are still receiving the treatment was 175 days. And the average time from initiations to drop-out of treatment for newly enrolled EMMT clients was 122 days. The 9-month retention rates of the clients were 52.1% and 60.9% at EMMT and MMT clinics, respectively.The effect on EMMT retention was the same as that of MMT. Establishment of EMMT clinics was an effective strategy to expand the coverage of MMT and increase the retention of opiate dependents in the rural areas of the counties.

Indexed as

AdolescentAdultAmbulatory Care FacilitiesAnalgesics, OpioidChinaCohort StudiesFemaleHeroin DependenceHumansMaleMethadoneOpiate Substitution TreatmentProspective StudiesQuality of LifeSubstance Abuse DetectionSurvival AnalysisAnalgesics, OpioidMethadone

Identifiers

PMID30461647
PMCPMC6392930
OpenAlexW2921430498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.