ArticleMedicine2018
The combination of Caprini risk assessment scale and thrombotic biomarkers to evaluate the risk of venous thromboembolism in critically ill patients.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Systematic review of venous thromboembolism risk categories derived from Caprini score.Journal of vascular surgery. Venous and lymphatic disorders · 2022Pooled it
- Construction and validation of the risk assessment scale for deep vein thrombosis in high altitude plateau areas.Frontiers in medicine · 2026Article
- Validation of the Caprini risk assessment model and efficacy of perioperative nutritional support + preventive nursing in reducing DVT among high-risk older adults undergoing hip fracture surgery: a two-phase study.Frontiers in medicine · 2026Article
- The predicted value for venous thromboembolism based on a modified model of caprini combined with fasting blood glucose and D-dimer: a retrospective study.BMC musculoskeletal disorders · 2025Article
- Risk stratification of deep vein thrombosis using caprini score among post-operative patients.Bioinformation · 2025Article
- Combined assessment of Caprini score, D-dimer, and thromboelastography for predicting deep venous thrombosis in lung cancer patients.American journal of cancer research · 2025Article
- Development of a predictive model for deep vein thrombosis in burn patients based on the Caprini Risk Assessment Scale.American journal of translational research · 2025Article
- Values of Caprini Risk Assessment Scale and D-Dimer for Predicting Venous Thromboembolism During Puerperium.International journal of women's health · 2024Article
- Application of the Caprini risk model in preventing deep venous thrombosis formation in patients with nephrotic syndrome.American journal of translational research · 2024Article
- Investigation and analysis of status of mechanical prevention of venous thrombosis in ICU.Nursing open · 2023Article
- Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis.Journal of clinical medicine · 2022Review
- Predicting pulmonary embolism among hospitalized patients with machine learning algorithms.Pulmonary circulation · 2022Article
- Predicting venous thromboembolism in hospitalized trauma patients: a combination of the Caprini score and data-driven machine learning model.BMC emergency medicine · 2021Article
- Influence of enhanced recovery after surgery (ERAS) on patients receiving lung resection: a retrospective study of 1749 cases.BMC surgery · 2021Article
- Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution.Experimental and therapeutic medicine · 2021Article
- Observational
- Development of a Risk Assessment Tool for Venous Thromboembolism among Hospitalized Patients in the ICU.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Derivation and External Validation of a Risk Assessment Model of Venous Thromboembolism in Hospitalized Chinese Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate the correlation between the Caprini risk assessment scale and plasma thrombosis biomarkers and estimate the validity of this method in identifying critically ill patients at high risk of venous thromboembolism (VTE).Patients with VTE who were admitted to the intensive care unit (ICU) department of West China Hospital SiChuan University from October 2016 to October 2017 were enrolled in this case-control study. We retrieved relative clinical data and laboratory test results included in the Caprini risk assessment scale to calculate the Caprini score and compared thrombosis biomarkers between various risk stratifications (low, moderate, high, and highest).A total of 151 critically ill patients were enrolled in our research, including 47 VTE and 94 non-VTE patients. The differences in Caprini score and levels of thrombosis biomarkers between the VTE and control group were significant. Thrombomodulin (TM) was positively correlated with Caprini score (R-value was .451, P < .05). Based on the receiver operating characteristic analysis, TM, tissue plasminogen activator-inhibitor complexes, D-dimer, and fibrinogen degradation products had a certain diagnostic efficiency in distinguishing VTE from others (P < .05). Using the logistic regression model, we identified that 5 risk factors, namely drinking history, major surgery (>3 hours), swollen legs (current), TM, and D-dimer, were independent factors for the occurrence of VTE in critically ill patients admitted in the ICU.Thrombosis markers were positively correlated with Caprini risk stratification. The combination of plasma markers and Caprini risk assessment scale can further increase the predictive value in critically ill patients with VTE.
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