ReviewPsychosomatic medicine
Psychological Therapy for Centralized Pain: An Integrative Assessment and Treatment Model.
Review in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Culturally Adapted Group-Based, Emotional Awareness and Expression Therapy Intervention - Hebrew (EAET-H) for Chronic Pain Patients Treated With Medical Cannabis in Israel - A Pilot Study
A Group-Based, Virtual Emotional Awareness and Expression Therapy Intervention - Hebrew (EAET-H) for Chronic Pain Patients Treated With Medical Cannabis in Israel - A Feasibility Study
Who cites it
54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- The effectiveness of psychological interventions on pain, disability, and psychological symptoms in whiplash-associated disorders: a systematic review and meta-analysis.BMC psychology · 2026Pooled it
- Prevalence of Depression and Anxiety Among Adults With Chronic Pain: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Co-Occurring Trauma and Non-Suicidal Self-Injury Among People With Chronic Pain: A Systematic Review.Current pain and headache reports · 2021Pooled it
- Psychological therapies for the management of chronic pain (excluding headache) in adults.The Cochrane database of systematic reviews · 2020Pooled it
- The effect of peer group management intervention on chronic pain intensity, number of areas of pain, and pain self-efficacy.Scandinavian journal of pain · 2025Trial
- Reattribution to Mind-Brain Processes and Recovery From Chronic Back Pain: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2023Trial
- Trial
- Mixed pain phenotypes in musculoskeletal disorders: mechanisms and management.Nature reviews. Rheumatology · 2026Review
- Targeting Brain-Body Processes in Postural Tachycardia Syndrome: A Pilot Trial of POts Reprocessing Therapy.Research square · 2026Article
- Feasibility and Preliminary Outcomes of a Brain/Body Intervention for Postural Tachycardia Syndrome (POTS): Pilot Trial of POts Reprocessing Therapy (PORT).Research square · 2026Article
- Proposed Conditions for Pain Reprocessing Therapy Readiness: Beyond Phenotyping Neuroplastic Pain.Current pain and headache reports · 2026Review
- An alternative "Port"? Rationale and development process for POts Reprocessing Therapy (PORT), a brain-body therapy for postural tachycardic syndrome (POTS).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Patient Perspectives on the Process and Outcome of Group Emotional Awareness and Expression Therapy for Chronic Pain.Journal of clinical psychology in medical settings · 2026Article
- Guided versus unguided internet-administered emotional awareness and expression therapy (I-EAET) for patients with persistent physical symptoms: A randomized trial.Internet interventions · 2026Article
- Exposure-based Interventions for Chronic Pain and Bodily Symptoms: A Special Interest Meeting Report.Behaviour research and therapy · 2026Article
- Emotion regulation variability and chronic pain: An ecological momentary assessment study.Behaviour research and therapy · 2026Article
- Understanding pain as threat or challenge: predictive roles of resilience, attachment, and sensory sensitivity.Pain medicine (Malden, Mass.) · 2026Article
- Development of a clinical prediction model for chronic post-surgical shoulder pain following arthroscopic rotator cuff repair: A prospective cohort study.Shoulder & elbow · 2026Article
- Virtual reality in chronic pain management: how do we galvanize a stagnant field?Pain management · 2025Article
- Non-Cyclical Mastalgia as a Central Sensitization Component: Implications for Multidisciplinary Treatment Approaches.Brain and behavior · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveChronic pain is a significant health problem that is increasing in prevalence, and advances in treatment are needed.
methodsWe briefly review the leading evidence-based psychological therapies for chronic pain-cognitive-behavioral and acceptance/mindfulness-based therapies-and examine several limitations and missing perspectives of these approaches. We review six lesser-known interventions that address these limitations, and we describe our integrative model for psychological assessment and treatment of centralized pain. We present a typical patient and describe how we apply this approach, along with challenges to its implementation and possible solutions to these challenges.
resultsGreater pain treatment efficacy may be possible if clinicians: (a) distinguish patients with primarily centralized (i.e., somatoform or nociplastic) pain from those with primarily peripheral (nociceptive, inflammatory, or neuropathic) pain; (b) acknowledge the capacity of the brain not only to modulate pain but also generate as well as attenuate or eliminate centralized pain; (c) consider the powerful role that adverse life experiences and psychological conflicts play in centralized pain; and (d) integrate emotional processing and interpersonal changes into treatment. Our integrative treatment involves delivering a progression of interventions, as needed, to achieve pain reduction: tailored pain neuroscience education, cognitive and mindfulness skills to decrease the pain danger alarm mechanism, behavioral engagement in avoided painful and other feared activities, emotional awareness and expression to reverse emotional avoidance and overcome trauma or psychological conflict, and adaptive communication to decrease interpersonal stress.
conclusionsThis integrative assessment and treatment model has the potential to substantially reduce and sometimes eliminate centralized pain by changing the cognitive, behavioral, emotional, and interpersonal processes that trigger and maintain centralized pain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.