Evidence map›Paper›PMID 30461420›Full record

ArticleeLife2018

Expanded genetic screening in

Kyung Won Kim, Ngang Heok Tang, Christopher A Piggott, Matthew G Andrusiak, Seungmee Park, Ming Zhu, Naina Kurup, Salvatore J Cherra, Zilu Wu, Andrew D Chisholm and 1 more

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. De novo NADCommunications biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The Expression and Function of Tubulin Isotypes inFrontiers in cell and developmental biology · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kyung Won KimSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.ORCID http://orcid.org/0000-0002-8252-6203
Ngang Heok TangSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Christopher A Piggott *Section of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Matthew G Andrusiak *Section of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Seungmee Park *Section of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Ming ZhuSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Naina KurupSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Salvatore J CherraSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Zilu WuSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.
Andrew D ChisholmSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.ORCID http://orcid.org/0000-0001-5091-0537
Yishi JinSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, United States.ORCID http://orcid.org/0000-0002-9371-9860

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Cytoskeletal dynamics in axon regenerationR01NS093588 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHISHOLM, ANDREW D, JIN, YISHI · 2015 to 2023
$3.7M
Development of a C. elegans model for axonal regenerationR01NS057317 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHISHOLM, ANDREW D · 2009 to 2013
$1.5M
Understanding the molecular mechanisms that maintain excitation-inhibition balance in neural circuitsR00NS097638 · NINDS · UNIVERSITY OF KENTUCKY · PI CHERRA, SALVATORE JAMES · 2019 to 2021
$738k
Development of a C.elegans model for axonal regenerationR56NS057317 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHISHOLM, ANDREW D, JIN, YISHI · 2014 to 2014
$388k
Understanding the molecular mechanisms that maintain excitation-inhibition balance in neural circuitsK99NS097638 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHERRA, SALVATORE JAMES · 2016 to 2017
$182k
CIHR MFE-146808NIH HHS K99 NS097638NIH HHS NS057317NIH HHS NS093588NIH HHS P40 OD010440NINDS NIH HHS K99 NS097638NINDS NIH HHS R00 NS097638NINDS NIH HHS R01 NS057317NINDS NIH HHS R01 NS093588NINDS NIH HHS R56 NS057317
6 · The paper itself

Abstract

The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury. Here, we report novel pathways in axon regeneration, identified by extending our previous function-based screen using the

Indexed as

Actin CytoskeletonAnimalsAxonsAxotomyCaenorhabditis elegansCaenorhabditis elegans ProteinsExtracellular MatrixGene Expression ProfilingGene Expression RegulationGene OntologyGenetic TestingKelch RepeatMembrane Transport ProteinsMicrotubulesMolecular Sequence AnnotationNADCaenorhabditis elegans ProteinsMembrane Transport ProteinsNADNicotinamide-Nucleotide Adenylyltransferaseaxon reconnection/fusionC. elegansKelch-domain proteinmembrane contact site (MCS)membrane transporterneuroscienceNMNATphospholipid metabolic enzyme

Identifiers

PMID30461420
PMCPMC6281318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.