Evidence map›Paper›PMID 30461399›Full record

ArticleJournal of the American Academy of Audiology2019

An Epidemiologic Study of the Association between Free Recall Dichotic Digits Test Performance and Vascular Health.

Mary E Fischer, Karen J Cruickshanks, Lauren K Dillard, David M Nondahl, Barbara E K Klein, Ronald Klein, James S Pankow, Ted S Tweed, Carla R Schubert, Dayna S Dalton and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Academy of Audiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Benefit of Musical Training for Speech Perception and Cognition Later in Life.Journal of speech, language, and hearing research : JSLHR · 2021
    Article
  4. Longitudinal Decline on the Dichotic Digits Test.American journal of audiology · 2020
    Article
  5. Macular Ganglion Cell-Inner Plexiform Layer as a Marker of Cognitive and Sensory Function in Midlife.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mary E FischerDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Karen J CruickshanksDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Lauren K DillardDepartment of Communication Sciences and Disorders, University of Wisconsin, Madison, WI.
David M NondahlDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Barbara E K KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Ronald KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
James S PankowDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN.
Ted S TweedDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Carla R SchubertDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Dayna S DaltonDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
Adam J PaulsenDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.
University of Wisconsin–Madison · USUniversity of Minnesota · US

Funding

FAMILIAL AND BIRTH COHORT EFFECTS ON THE AGING SENSESR01AG021917 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CRUICKSHANKS, KAREN J · 2004 to 2018
$25.2M
THE EPIDEMIOLOGY OF AGE-RELATED OCULAR DISEASEU10EY006594 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI GANGNON, RONALD E · 1987 to 2018
$17.3M
Epidemiology of Age-related Hearing LossR37AG011099 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CRUICKSHANKS, KAREN J · 2009 to 2018
$7.4M
NEI NIH HHS U10 EY006594NIA NIH HHS R01 AG021917NIA NIH HHS R37 AG011099
6 · The paper itself

Abstract

backgroundAssociations between vascular health-related factors and hearing loss defined using audiometric pure-tone thresholds have been found. Studies have not focused on a potential relationship between vascular health-related factors and central auditory processing. PURPOSE: The aim of this study was to evaluate, on a population level, the relationship of vascular health-related factors with central auditory function. RESEARCH

designA cross-sectional, population study. STUDY SAMPLE: Subjects were participants in the Epidemiology of Hearing Loss Study (EHLS) or the Beaver Dam Offspring Study (BOSS)-prospective studies of aging and sensory loss. BOSS participants were the adult offspring of participants in the EHLS. Participants who completed the Dichotic Digits Test (DDT) during the fourth examination period of the EHLS (2008-2010) or the second examination period of the BOSS (2010-2013) were included (n = 3,655, mean age = 61.1 years). DATA COLLECTION AND ANALYSIS: The DDT-free recall test was conducted using 25 sets of triple-digit pairs at a 70 dB HL presentation level. The total number of correctly repeated digits from the right and left ears was converted to a percentage correct and used as an outcome. The percentage correct in the left ear was subtracted from the percentage correct in the right ear and used as an outcome. Vascular health-related measures obtained during the examination included blood pressure, mean carotid intima-media thickness, femoral pulse wave velocity (PWV), hemoglobin A1C, and non-high-density lipoprotein (HDL) cholesterol, and, in the EHLS participants, C-reactive protein and interleukin-6. Information on vascular health-related history and behaviors was self-reported. General linear modeling produced estimates of the age- and sex-adjusted least squares means for each vascular factor, and multiple linear regression was used for multivariable modeling of each outcome.

resultsAfter multivariable adjustment, participants with diabetes had a significantly lower (worse) mean DDT-free recall total score (-2.08 percentage points, p < 0.001) than those without diabetes. Participants who exercised at least once per week had a significantly higher (better) mean DDT-free recall total score (+1.07 percentage points, p < 0.01) than those who did not exercise at least once per week. Alcohol consumption was associated with a higher DDT-free recall total score (+0.15 percentage points per +25 g ethanol, p < 0.01). In multivariable modeling of the right-left ear difference in DDT-free recall scores, participants with a history of cardiovascular disease (CVD) or higher PWV demonstrated significantly larger differences (CVD: +3.11 percentage points, p = 0.02; PWV: +0.36 percentage points per 1 m/sec, p < 0.01). Higher levels of non-HDL cholesterol were associated with smaller right-left ear differences (-0.22 percentage points per 10 mg/dL, p = 0.01). Adjustment for handedness did not affect the results.

conclusionsVascular health-related factors may play a role in central auditory function.

Indexed as

Dichotic Listening TestsHearing LossMental RecallAdultAgedAged, 80 and overCardiovascular DiseasesCross-Sectional StudiesEpidemiologic StudiesFemaleHearingHumansMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID30461399
PMCPMC6251763
OpenAlexW2791956570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.