Evidence map›Paper›PMID 30461353›Full record

ArticleThe neuroradiology journal2019

Discrimination of epileptogenic lesions and perilesional white matter using diffusion tensor magnetic resonance imaging.

Alexander Rau, Elias Kellner, Niels A Foit, Niklas Lützen, Dieter H Heiland, Andreas Schulze-Bonhage, Marco Reisert, Valerij G Kiselev, Marco Prinz, Horst Urbach and 1 more

Abstract read
In one paragraph

Article in The neuroradiology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander Rau1 Department of Neuroradiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Elias Kellner2 Medical Physics, Department of Radiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Niels A Foit3 Department of Neurosurgery, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Niklas Lützen1 Department of Neuroradiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Dieter H Heiland3 Department of Neurosurgery, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Andreas Schulze-Bonhage4 Epilepsy Centre, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Marco Reisert2 Medical Physics, Department of Radiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Valerij G Kiselev2 Medical Physics, Department of Radiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Marco Prinz5 Institute of Neuropathology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Horst Urbach1 Department of Neuroradiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Irina Mader1 Department of Neuroradiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate whether ganglioglioma (GGL), dysembryoplastic neuroepithelial tumour (DNET) and FCD (focal cortical dysplasia) are distinguishable through diffusion tensor imaging. Additionally, it was investigated whether the diffusion measures differed in the perilesional (pNAWM) and in the contralateral normal appearing white matter (cNAWM). Six GGLs, eight DNETs and seven FCDs were included in this study. Quantitative diffusion measures, that is, axial, radial and mean diffusivity and fractional anisotropy, were determined in the lesion identified on isotropic T2 or FLAIR-weighted images and in pNAWM and cNAWM, respectively. DNET differed from FCD in mean diffusivity, and GGL from FCD in radial diffusivity. Both types of glioneuronal tumours were different from pNAWM in fractional anisotropy and radial diffusivity. For identifying the tumour edges, threshold values for tumour-free tissue were investigated with receiver operating characteristic analyses: tumour could be separated from pNAWM at a threshold ≤ 0.32 (fractional anisotropy) or ≥ 0.56 (radial diffusivity) *10

Indexed as

AdolescentAdultAgedAnisotropyBrain DiseasesChildContrast MediaDiagnosis, DifferentialDiffusion Tensor ImagingEpilepsyFemaleGangliogliomaGermanyHumansMaleMalformations of Cortical Development, Group IContrast Mediadiffusion tensor imagingEpilepsy associated lesionsfocal cortical dysplasialong-term epilepsy-associated tumoursMRI

Identifiers

PMID30461353
PMCPMC6327366

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.