Evidence map›Paper›PMID 30461057›Full record

Observational studyJournal of clinical laboratory analysis2019

Prevalence of food-allergen and aeroallergen sensitization among people in Sichuan, Western China: An 8-year observational study.

Zhuochun Huang, Weihua Feng, Wei Wei, Bin Yang, Lanlan Wang

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Pollen-Food Allergy Syndrome in China: Current Knowledge and Future Research Needs.International archives of allergy and immunology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Food allergies in older people: An emerging health problem.The World Allergy Organization journal · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Allergen Analysis of 4622 Children with Allergic Diseases in Shaanxi Province].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021
    Article
  13. Article
  14. China Consensus Document on Allergy Diagnostics.Allergy, asthma & immunology research · 2021
    Review
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhuochun HuangDepartment of Lab Medicine, West China Hospital, Sichuan University, Chengdu, China.
Weihua FengDepartment of Lab Medicine, West China Hospital, Sichuan University, Chengdu, China.
Wei WeiWest China Medical School, Sichuan University, Chengdu, China.
Bin YangDepartment of Lab Medicine, West China Hospital, Sichuan University, Chengdu, China.
Lanlan WangDepartment of Lab Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0002-0601-1275
Sichuan University · CNWest China Medical Center of Sichuan University · CN

Funding

Foundation of Science and Technology bureau of Sichuan Province 2017FZ0070, 2017SZ0150, 2018FZ0106National Natural Science Foundation of China 81772258, 81501816, 81601830
6 · The paper itself

Abstract

backgroundIdentifying the distribution of allergens is invaluable to effective diagnosis and treatment of allergic disease. The present study aims to analyze the epidemiology of allergens in Sichuan, Western China.

methodsA total of 14 030 participants including 8031 men and 5999 women were enrolled in this study during 2007-2014 in West China Hospital. An assay testing for the presence of allergen-specific IgE was used to identify highly immunogenic allergens.

resultsOf the 14 030 total participants, 3470 (24.72%) were sensitive to at least one of tested allergens. The most immunogenic allergens were mite mix (1876, 13.38%), crab (876, 6.24%), sea-fish mix (865, 6.16%), house dust (355, 2.54%), and cockroach (292, 2.08%). The differences between population of participants who were sensitive to food allergens and aeroallergens were statistically significant in 0 to 10, 11 to 20, 21 to 30, 41 to 50, and 51 to 60 year-old age-groups (all P < 0.05). Distributions of three food allergens and two aeroallergens were significantly different between male and female participants. There was also an increase in sensitization to cow's milk, mutton, sea-fish, and mould that was observed in the 71 to 90 year-old group.

conclusionThe most common allergens presented in Sichuan were observed to be mites, crab, sea-fish, and house dust. There was an observable difference in sensitivity to five allergens between males and females. Additionally, aeroallergens appeared to have a greater immunogenic effect in younger populations while the elderly presented with increased sensitization to specific allergens, suggesting that specific allergens' immunogenicity was age-dependent.

Indexed as

AllergensAdolescentAdultAgedAged, 80 and overChildChild, PreschoolChinaCohort StudiesFemaleFood HypersensitivityHumansHypersensitivityInfantMaleMiddle AgedAllergensaeroallergenagefood allergengenderprevalencesensitization

Identifiers

PMID30461057
PMCPMC6818623
OpenAlexW2900705897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.