ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2019
Pocket related complications following cardiac electronic device implantation in patients receiving anticoagulation and/or dual antiplatelet therapy: prospective evaluation of different preventive strategies.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Effect of pocket compression device on pocket hematoma after cardiac implantable electronic device implantation.Scientific reports · 2025Trial
- Effect of a pocket compression device on hematomas, skin reactions, and comfort in patients receiving a cardiovascular implantable electronic device: a randomized controlled trial.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Trial
- Safety study of permanent pacemaker implantation after TAVI under multiple antithrombotic therapies.BMC cardiovascular disorders · 2026Article
- Risk Factors and Preventing Strategies of Pocket Hematoma After Cardiac Implantable Electronic Device Implantation: A Systematic Review.Journal of cardiovascular development and disease · 2025Review
- Efficacy of a novel compression tool in preventing complications following device implantation.Open heart · 2025Article
- Pocket compression devices: a novel, non-invasive, and cost-effective approach to pocket hematoma resolution.Annals of medicine and surgery (2012) · 2025Article
- Wide-awake local anesthesia during insertion of cardiac implantable electronic devices: a randomized study.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Real-world survey of post-operative cardiac implantable electronic device (CIED) complications reported by the electrophysiology team in 2022.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Article
- Prevention of device-related infections in patients with cancer: Current practice and future horizons.CA: a cancer journal for clinicians · 2023Review
- Review
- Effect of a Novel Pocket Compression Device on Hematomas Following Cardiac Electronic Device Implantation in Patients Receiving Direct Oral Anticoagulants.Frontiers in cardiovascular medicine · 2022Article
- Application and outlook of topical hemostatic materials: a narrative review.Annals of translational medicine · 2021Review
- Very early discharge after cardiac implantable electronic device implantations: is this the future?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe sought to assess the safety and effectiveness of three different devices: (1) vacuum drainage system, (2) hemostatic gelatin sponge (Stypro®), and (3) compression device (Premofix®) compared to standard of care (control) in patients undergoing cardiac implantable electronic device (CIED) implantation receiving anticoagulation and/or dual antiplatelet therapy (DAPT).
methodsWe enrolled all consecutive patients admitted for first permanent CIED implantation receiving anticoagulation and/or DAPT into a prospective registry. The primary endpoint (1°EP) was a composite of hematoma grade > 1 and pocket infection.
resultsWe included 406 patients (median age 73 years, 71% male) of whom 103 (25%) received a vacuum drainage system, 99 (24%) received Stypro®, 103 (25%) received Premofix®, and 101 (25%) were in the control group. One hundred eighty patients (44%) were treated with anticoagulation (median INR 2.0), 176 (43%) received DAPT, and 50 (12%) both. The occurrence of the 1°EP was reduced by Stypro® (hazard ratio (HR) 0.38 (95% confidence interval (CI) 0.16-0.94) and Premofix® (HR: 0.37 (95% CI 0.15-0.90)) compared to controls (p < 0.05 for both). The incidence of hematoma grade 2 or 3 was exclusively lowered by Premofix® compared to control (6% versus 15%; p < 0.05) and was not affected by the type of CIED, INR (≥ 2.5 versus < 2.5), body mass index (≥ 30 versus < 30), or CIED implantation under anticoagulation plus DAPT. The vacuum drainage system did not affect the 1°EP or the incidence of hematoma.
conclusionsIn patients receiving anticoagulation and/or DAPT undergoing CIED implantation, the use of Premofix® and Stypro® significantly lowered the 1°EP occurrence compared to control. Premofix® additionally lowered the frequency of pocket hematomas >grade 1.
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