Evidence map›Paper›PMID 30460484›Full record

ArticleCognitive, affective & behavioral neuroscience2019

Socioeconomic disadvantage, brain morphometry, and attentional bias to threat in middle childhood.

Alexander J Dufford, Hannah Bianco, Pilyoung Kim

Abstract read
In one paragraph

Article in Cognitive, affective & behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Examination of poverty trajectories and brain volume as predictors of adolescent depression.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
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  18. The Neuroscience of Socioeconomic Inequality.Current opinion in behavioral sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander J DuffordDepartment of Psychology, University of Denver, Frontier Hall, Room 331, 2155 S. Race St, Denver, CO, 80208, USA. alexander.dufford@du.edu.ORCID 0000-0002-8846-5624
Hannah BiancoDepartment of Psychology, University of Denver, Frontier Hall, Room 331, 2155 S. Race St, Denver, CO, 80208, USA.
Pilyoung KimDepartment of Psychology, University of Denver, Frontier Hall, Room 331, 2155 S. Race St, Denver, CO, 80208, USA.

Funding

Prenatal Pathways for Poverty’s Influence on the Brains of Two GenerationsR01HD090068 · NICHD · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KIM, PILYOUNG · 2017 to 2022
$2.8M
The influence of in utero cannabis exposure on neonatal brain morphology and structural connectivityR21DA043833 · NIDA · UNIVERSITY OF COLORADO DENVER · PI CRUME, TESSA L, KIM, PILYOUNG · 2018 to 2019
$431k
Cannabis Use during Pregnancy, Maternal Brain, and Mother-Infant RelationshipsR21DA046556 · NIDA · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KIM, PILYOUNG · 2018 to 2019
$422k
Poverty, Chronic Stress and Neural Regulation of Maternal Mood and ParentingR21HD078797 · NICHD · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KIM, PILYOUNG · 2014 to 2015
$405k
NICHD NIH HHS R01 HD090068NICHD NIH HHS R21 HD078797NIDA NIH HHS R21 DA043833NIDA NIH HHS R21 DA046556
6 · The paper itself

Abstract

Socioeconomic disadvantage is associated with higher rates of psychopathology as well as hippocampus, amygdala and prefrontal cortex structure. However, little is known about how variations in brain morphometry are associated with socio-emotional risks for mood disorders in children growing up in families experiencing low income. In the current study, using structural magnetic resonance imaging, we examined the relationship between socioeconomic disadvantage and gray matter volume in the hippocampus, amygdala, and ventrolateral prefrontal cortex in a sample of children (n = 34) in middle childhood. Using an affective dot probe paradigm, we examined the association between gray matter volume in these regions and attentional bias to threat, a risk marker for mood disorders including anxiety disorders. We found that lower income-to-needs ratio was associated with lower bilateral hippocampal and right amygdala volume, but not prefrontal cortex volumes. Moreover, lower attentional bias to threat was associated with greater left hippocampal volume. We provide evidence of a relationship between income-related variations in brain structure and attentional bias to threat, a risk for mood disorders. Therefore, these findings support an environment-morphometry-behavior relationship that contributes to the understanding of income-related mental health disparities in childhood.

Indexed as

Attentional BiasSocioeconomic FactorsAmygdalaBrainChildFemaleGray MatterHippocampusHumansMagnetic Resonance ImagingMaleOrgan SizePovertyPrefrontal CortexAmygdalaAttentional biasFamily incomeHippocampusMiddle childhoodMorphometry

Identifiers

PMID30460484
PMCPMC6951020

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.