Evidence map›Paper›PMID 30460457›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2019

Behavioral and Cognitive Improvement Induced by Novel Imidazoline I

Christian Griñán-Ferré, Foteini Vasilopoulou, Sònia Abás, Sergio Rodríguez-Arévalo, Andrea Bagán, Francesc X Sureda, Belén Pérez, Luis F Callado, Jesús A García-Sevilla, M Julia García-Fuster and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Christian Griñán-FerréPharmacology Section, Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Foteini VasilopoulouPharmacology Section, Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Sònia AbásLaboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Sergio Rodríguez-ArévaloLaboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Andrea BagánLaboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Francesc X SuredaPharmacology Unit, Faculty of Medicine and Health Sciences, University of Rovira and Virgili, C./St. Llorenç 21, 43201, Reus, Tarragona, Spain.
Belén PérezDepartament of Pharmacology, Therapeutic and Toxicology, Autonomous University of Barcelona, 08193, Barcelona, Spain.
Luis F CalladoDepartment of Pharmacology, University of the Basque Country, UPV/EHU, 48940, Leioa, Bizkaia, Spain.
Jesús A García-SevillaLaboratory of Neuropharmacology, IUNICS and IdISBa, University of the Balearic Islands (UIB), Cra. Valldemossa km 7.5, 07122, Palma de Mallorca, Spain.
M Julia García-FusterLaboratory of Neuropharmacology, IUNICS and IdISBa, University of the Balearic Islands (UIB), Cra. Valldemossa km 7.5, 07122, Palma de Mallorca, Spain.
Carmen EscolanoLaboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.
Mercè PallàsPharmacology Section, Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain. pallas@ub.edu.ORCID 0000-0003-3095-4254
Universitat de Barcelona · ESHealth Research Institute of the Balearic Islands · ESUniversitat Autònoma de Barcelona · ESUniversitat Rovira i Virgili · ESUniversity of the Basque Country · ES

Funding

Association Belge contre les Maladies Neuro-Musculaires (BE) 2017SGR106Basque Government IT616/13Ministerio de Economía y Competitividad of Spain SAF2014-55903-RMinisterio de Economía y Competitividad of Spain SAF2016-33307
6 · The paper itself

Abstract

As populations increase their life expectancy, age-related neurodegenerative disorders such as Alzheimer's disease have become more common. I

Indexed as

AgingAmyloid beta-Protein PrecursorAnimalsApoptosisBehavior, AnimalCognitionDisease Models, AnimalFemaleHippocampusImidazoline ReceptorsMiceOxidative StressRecognition, PsychologyAmyloid beta-Protein Precursorimidazoline receptor 2Imidazoline Receptors(2-imidazolin-4-yl)phosphonatesAgingBehaviorCognitionImidazoline I2 receptorsNeurodegenerationNeuroprotection

Identifiers

PMID30460457
PMCPMC6554384
OpenAlexW2901896340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.