Evidence map›Paper›PMID 30460450›Full record

Observational studyJournal of neurology2019

Isolated seizures are a common early feature of paraneoplastic anti-GABA

Aurélien Maureille, Tanguy Fenouil, Bastien Joubert, Géraldine Picard, Véronique Rogemond, Anne-Laurie Pinto, Laure Thomas, François Ducray, Isabelle Quadrio, Dimitri Psimaras and 4 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Autoimmune "Atypical" Atypical Parkinsonism: Anti-GABAMovement disorders clinical practice · 2025
    Article
  5. GABAMedComm · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Lambert-Eaton Myasthenic Syndrome Complicated by Anti-GABAInternal medicine (Tokyo, Japan) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Autoimmune encephalitis: the first observational study from Iran.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Observational
  17. Review
  18. GABACurrent topics in behavioral neurosciences · 2022
    Article
  19. GABACurrent topics in behavioral neurosciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Aurélien MaureilleFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Tanguy FenouilService d'anatomopathologie, Hospices civils de Lyon, Lyon, France.
Bastien JoubertFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Géraldine PicardFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Véronique RogemondFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Anne-Laurie PintoFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Laure ThomasFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
François DucrayFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Isabelle QuadrioService de Neurobiologie, Hospices civils de Lyon, Lyon, France.
Dimitri PsimarasFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Giulia BerzeroFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Jean-Christophe AntoineFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Virginie DesestretFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France.
Jérôme HonnoratFrench Reference Center on Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Neuro-Oncologie, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677, Bron Cedex, France. jerome.honnorat@chu-lyon.fr.
Hospices Civils de Lyon · FRHôpital Pierre Wertheimer · FRCentre National de la Recherche Scientifique · FRInstitut NeuroMyoGène · FR

Funding

Agence Nationale de la Recherche ANR-14-CE15-0001-MECANOFédération pour la Recherche sur le Cerveau FRC-Neurodon2014Fondation pour la recherche médicale DQ20170336751
6 · The paper itself

Abstract

objectiveTo report the clinical features and long-term outcome of 22 newly diagnosed paraneoplastic patients with GABA

methodsRetrospective clinical study of CSF-confirmed cases of GABA

resultsWe identified 22 patients (4 female) with GABA

conclusionParaneoplastic GABA

Indexed as

AgedAged, 80 and overAmnesia, AnterogradeAutoantibodiesEncephalitisFemaleHumansImmunotherapyLung NeoplasmsMaleMiddle AgedParaneoplastic Syndromes, Nervous SystemReceptors, GABA-BRetrospective StudiesSeizuresSmall Cell Lung CarcinomaAutoantibodiesReceptors, GABA-BEpilepsyGABAB receptor autoantibodiesParaneoplatic neurological syndromesSmall cell lung cancerStatus epilepticus

Identifiers

PMID30460450
OpenAlexW2900547896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.