Evidence map›Paper›PMID 30460347›Full record

ArticleAnnals of gastroenterological surgery2018

Clinical significance of the globulin-to-albumin ratio for prediction of postoperative survival in patients with colorectal cancer.

Hiroyuki Hachiya, Mitsuru Ishizuka, Kazutoshi Takagi, Yoshimi Iwasaki, Norisuke Shibuya, Yusuke Nishi, Taku Aoki, Keiichi Kubota

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Retrospective study on the potential of albumin/globulin ratio as a prognostic biomarker for oral cavity cancer patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  8. Article
  9. Article
  10. Predictive Values of the Selected Inflammatory Indexes in Colon Cancer.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroyuki HachiyaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID 0000-0003-0508-3135
Mitsuru IshizukaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID 0000-0003-3241-1480
Kazutoshi TakagiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Yoshimi IwasakiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Norisuke ShibuyaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID 0000-0003-1367-295X
Yusuke NishiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Taku AokiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Keiichi KubotaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimA previous study has revealed that the albumin/globulin ratio (GAR) before treatment is a predictor of cancer-specific survival in patients with colorectal cancer (CRC). The aim of the present study was to investigate the clinical significance of GAR for prediction of postoperative survival in patients with CRC.

methodsNine hundred and forty-one patients who had undergone elective CRC surgery were enrolled. Uni- and multivariate analysis models were performed to detect the clinical characteristics that were most closely associated with overall survival (OS). All recommended cutoff values were defined using receiver operating characteristic curve (ROC) analyses. Kaplan-Meier analysis was used to compare the OS curves between the high GAR (GAR > 0.83) and low GAR (GAR ≤ 0.83) groups.

resultsMultivariate analysis using eight clinical characteristics selected by univariate analyses showed that the GAR was associated with OS (>0.83/≤0.83) (hazard ratio [HR], 1.979; 95% CI, 1.321-2.966;

conclusionGlobulin-to-albumin ratio is a useful predictor of postoperative survival in patients with CRC.

Indexed as

biomarkercolorectal cancerglobulin‐to‐albumin ratioinflammation‐based prognostic systemsystemic inflammatory response

Identifiers

PMID30460347
PMCPMC6236099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.