Evidence map›Paper›PMID 30460346›Full record

ArticleAnnals of gastroenterological surgery2018

Long-term outcomes following restorative proctocolectomy ileal pouch-anal anastomosis in pediatric ulcerative colitis patients: Multicenter national study in Japan.

Hiroki Ikeuchi, Motoi Uchino, Akira Sugita, Kitaro Futami, Kouhei Fukushima, Keisuke Hata, Kazutaka Koganei, Masato Kusunoki, Keiichi Uchida, Riichiro Nezu and 9 more

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

19 authors.

Hiroki IkeuchiDepartment of Inflammatory Bowel Disease Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan.ORCID 0000-0001-9144-5782
Motoi UchinoDepartment of Inflammatory Bowel Disease Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan.
Akira SugitaDepartment of Inflammatory Bowel Disease Yokohama Municipal Citizen's Hospital Yokohama Kanagawa Japan.
Kitaro FutamiDepartment of Surgery Fukuoka University Chikushi Hospital Chikushino, Fukuoka Japan.
Kouhei FukushimaDepartment of Surgical and Molecular Pathophysiology Tohoku University Graduate School of Medicine Sendai Miyagi Japan.
Keisuke HataDepartment of Surgical Oncology The University of Tokyo Tokyo Japan.
Kazutaka KoganeiDepartment of Inflammatory Bowel Disease Yokohama Municipal Citizen's Hospital Yokohama Kanagawa Japan.
Masato KusunokiDepartment of Gastrointestinal and Pediatric Surgery Mie University Graduate School of Medicine Tsu Mie Japan.
Keiichi UchidaDepartment of Gastrointestinal and Pediatric Surgery Mie University Graduate School of Medicine Tsu Mie Japan.
Riichiro NezuDepartment of Surgery Nishinomiya Municipal Center Hospital Nishinomiya Hyogo Japan.
Hideaki KimuraInflammatory Bowel Disease Center Yokohama City University Medical Center Yokohama Kanagawa Japan.
Kenichi TakahashiColoproctology Center Tohoku Rosai Hospital Sendai Miyagi Japan.
Michio ItabashiInstitute of Gastroenterology Tokyo Women's Medical University Hospital Tokyo Japan.
Hitoshi KameyamaDivision of Digestive and General Surgery Niigata University Niigata Japan.
Daijiro HigashiDepartment of Surgery Fukuoka University Chikushi Hospital Chikushino, Fukuoka Japan.
Fumikazu KoyamaDepartment of Surgery Nara Medical University Kashihara, Nara Japan.
Takeshi UedaDepartment of Surgery Nara Medical University Kashihara, Nara Japan.
Tsunekazu MizushimaDepartment of Therapeutics for Inflammatory Bowel Diseases Osaka University Graduate School of Medicine Suita, Osaka Japan.ORCID 0000-0002-0825-6823
Yasuo SuzukiDepartment of Internal Medicine Toho University Sakura Medical Center Sakura Chiba Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have investigated surgical outcomes following a colectomy in pediatric patients with ulcerative colitis (UC). PURPOSE: This study aimed to determine long-term outcomes in a large cohort of pediatric patients who underwent proctocolectomy with ileal pouch-anal anastomosis (IPAA) for UC.

methodsPediatric patients (<17 years old) who underwent surgery at 12 different hospitals in Japan between May 1979 and March 2015 were included in this study. Information was obtained by the use of a questionnaire survey.

resultsThere were 113 (53.3%) male and 99 (46.7%) female pediatric patients. The most common indication for elective surgery was failure of medical management, whereas emergency surgery was carried out for fulminant cases. A hand-sewn IPAA was used with a mucosectomy in 112 (52.8%), stapled anastomosis in 93 (43.9%), and not specified in 7 (3.3%) patients. Small bowel obstruction and surgical site infection were the most frequent early postoperative complications (POC), whereas pouchitis, small bowel obstruction, and perianal fistula were frequent late POC. The most common late POC was pouchitis, found in 38 (17.9%) of the patients, whereas pouch failure was noted in 11 patients at the latest follow-up examination. Cumulative pouch survival rate after 10 years was 91.7%. There were no significant differences regarding gender or anastomotic procedure in relation to cumulative pouch survival rate.

conclusionTo avoid pouch failure following an IPAA procedure, it is important to recognize that pouchitis or an anal fistula may lead to this condition in pediatric UC patients.

Indexed as

ileal pouch‐anal anastomosispediatricpouch failurepouch functioning rateulcerative colitis

Identifiers

PMID30460346
PMCPMC6236100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.