ReviewAnnals of translational medicine2018
Dead space in acute respiratory distress syndrome.
Review in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Perioperative Blood Biomarkers of Infectious and Non-Infectious Postoperative Pulmonary Complications: A Narrative Review.Journal of clinical medicine · 2026Review
- Predicting early prone position ventilation responsiveness in patients with acute respiratory distress syndrome based on electrical impedance tomography: a prospective study.Critical care (London, England) · 2025Observational
- Lung-protective ventilation strategy in acute respiratory distress syndrome: a critical reappraisal of current practice.Critical care (London, England) · 2025Review
- Time-varying intensity of ventilatory inefficiency and mortality in patients with acute respiratory distress syndrome.Annals of intensive care · 2025Article
- The Ventilatory Ratio as a Predictor of Successful Weaning from a Veno-Venous Extracorporeal Membrane Oxygenator.Journal of clinical medicine · 2024Article
- Prognostic value of time-varying dead space estimates in mechanically ventilated patients with acute respiratory distress syndrome.Journal of intensive medicine · 2024Article
- Improved oxygenation in prone positioning of mechanically ventilated patients with COVID-19 acute respiratory distress syndrome is associated with decreased pulmonary shunt fraction: a prospective multicenter study.European journal of medical research · 2023Observational
- Epidemiology, Ventilation Management and Outcomes of COPD Patients Receiving Invasive Ventilation for COVID-19-Insights from PRoVENT-COVID.Journal of clinical medicine · 2023Article
- The relationship between ventilatory ratio (VR) and 28-day hospital mortality by restricted cubic splines (RCS) in 14,328 mechanically ventilated ICU patients.BMC pulmonary medicine · 2022Article
- Lung Mechanics Over the Century: From Bench to Bedside and Back to Bench.Frontiers in physiology · 2022Review
- Bedside estimates of dead space using end-tidal COCritical care (London, England) · 2021Article
- Personalized mechanical ventilation in acute respiratory distress syndrome.Critical care (London, England) · 2021Review
- Observational study of the use of recombinant tissue-type plasminogen activator in COVID-19 shows a decrease in physiological dead space.ERJ open research · 2020Article
- Time Course of Evolving Ventilator-Induced Lung Injury: The "Shrinking Baby Lung".Critical care medicine · 2020Article
- Protective ventilation from ICU to operating room: state of art and new horizons.Korean journal of anesthesiology · 2020Review
- [Clinical experience of high-flow nasal cannula oxygen therapy in severe COVID-19 patients].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020Article
- Respiratory drive in the acute respiratory distress syndrome: pathophysiology, monitoring, and therapeutic interventions.Intensive care medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dead space is the portion of each tidal volume that does not take part in gas exchange and represents a good global index of the efficiency of the lung function. Dead space is not routinely measured in critical care practice, because the difficulties in in interpreting capnograms and the different methods of calculations. Different dead space indices can provide useful information in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) patients, where changes in microvasculature are the main determinants for the increase in dead space and consequently a worsening of the outcome. Lung recruitment is a dynamic process that combines recruitment manoeuvres (RMs) with positive end expiratory pressure (PEEP) and low Vt to recruit collapsed alveoli. Dead space guided recruitment allows avoiding regional overdistension or reduction in cardiac output in critical care patients with ALI or ARDS. Different patterns of ventilation affect also CO
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