Evidence map›Paper›PMID 30460231›Full record

ArticleFrontiers in bioengineering and biotechnology2018

Make It Simple: (SR-A1+TLR7) Macrophage Targeted NANOarchaeosomes.

Federico Leonel Parra, Ayelen Tatiana Caimi, Maria Julia Altube, Diego Esteban Cargnelutti, Mónica Elba Vermeulen, Marcelo Alexandre de Farias, Rodrigo Villares Portugal, Maria Jose Morilla, Eder Lilia Romero

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Article
  8. Roles of TLR7 inFrontiers in cellular and infection microbiology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Federico Leonel ParraDepartamento de Ciencia y Tecnología, Nanomedicine Research & Development Center, Universidad Nacional de Quilmes, Bernal, Argentina.
Ayelen Tatiana CaimiDepartamento de Ciencia y Tecnología, Nanomedicine Research & Development Center, Universidad Nacional de Quilmes, Bernal, Argentina.
Maria Julia AltubeDepartamento de Ciencia y Tecnología, Nanomedicine Research & Development Center, Universidad Nacional de Quilmes, Bernal, Argentina.
Diego Esteban CargneluttiCentro Científico y Tecnológico de Mendoza, Instituto de Medicina y Biología Experimental de Cuyo, Consejo Nacional de Investigaciones Científicas y Técnicas, Mendoza, Argentina.
Mónica Elba VermeulenInstituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Ciudad Autónoma de Buenos Aires, Argentina.
Marcelo Alexandre de FariasBrazilian Nanotechnology National Laboratory, CNPEM, Campinas, Brazil.
Rodrigo Villares PortugalBrazilian Nanotechnology National Laboratory, CNPEM, Campinas, Brazil.
Maria Jose MorillaDepartamento de Ciencia y Tecnología, Nanomedicine Research & Development Center, Universidad Nacional de Quilmes, Bernal, Argentina.
Eder Lilia RomeroDepartamento de Ciencia y Tecnología, Nanomedicine Research & Development Center, Universidad Nacional de Quilmes, Bernal, Argentina.
National University of Quilmes · ARBrazilian Center for Research in Energy and Materials · BRConsejo Nacional de Investigaciones Científicas y Técnicas · ARExperimental Medicine and Biology Institute · ARLaboratório Nacional de Nanotecnologia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperhalophilic archaebacteria exclusively produce sn2,3 diphytanylglycerol diether archaeolipids, unique structures absent in bacteria and eukaryotes. Nanovesicles made of archaeolipids known as nanoarchaeosomes (nanoARC), possess highly stable bilayers, some of them displaying specific targeting ability. Here we hypothesize that nanoARC made from

Indexed as

archaeolipidsendocytic internalizationinterleukin 6scavenger receptortoll like receptor

Identifiers

PMID30460231
PMCPMC6232313
OpenAlexW2899631806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.