Evidence map›Paper›PMID 30460154›Full record

ArticleBiomedical optics express2018

Noninvasive label-free detection of circulating white and red blood clots in deep vessels with a focused photoacoustic probe.

Mazen A Juratli, Yulian A Menyaev, Mustafa Sarimollaoglu, Alexander V Melerzanov, Dmitry A Nedosekin, William C Culp, James Y Suen, Ekaterina I Galanzha, Vladimir P Zharov

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05301348 (In Vivo Detection of Circulating Clots in Patients With Thromboembolism), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05301348 narecruitingnot on this mapstarted 2023, after this paper: background citation

In Vivo Detection of Circulating Clots in Patients With Thromboembolism

TypeinterventionalSponsorUniversity of ArkansasRan2023 to 2027Enrolled30ConditionsThromboembolismArmsPhotoacoustic Flow Cytometry
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. A Deep Learning Approach to Photoacoustic Wavefront Localization in Deep-Tissue Medium.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020
    Article
  9. The Impact of Kinase Insert Domain (KDR) Gene Polymorphism rs2305948 on Clopidogrel Resistance in Iraqi Patients Undergoing Elective Percutaneous Coronary Intervention (PCI).Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mazen A JuratliDepartment of General and Visceral Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, 60323, Germany.
Yulian A MenyaevArkansas Nanomedicine Center, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Mustafa SarimollaogluArkansas Nanomedicine Center, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Alexander V MelerzanovMoscow Institute of Physics and Technology (MIPT), Moscow Region 141700, Russia.
Dmitry A NedosekinDepartment of General and Visceral Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, 60323, Germany.
William C CulpDepartment of Radiology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
James Y SuenDepartment of Otolaryngology, Head and Neck Surgery, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Ekaterina I GalanzhaArkansas Nanomedicine Center, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Vladimir P ZharovArkansas Nanomedicine Center, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · USGoethe University Frankfurt · DESaratov State University · RUMoscow Institute of Physics and Technology · RU

Funding

In vivo real-time detection of circulating melanoma cellsR01CA131164 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI SUEN, JAMES · 2009 to 2019
$3.1M
Photoswitchable nanoprobes for in vivo flow cytometryR01EB017217 · NIBIB · UNIV OF ARKANSAS FOR MED SCIS · PI ZHAROV, VLADIMIR P · 2014 to 2017
$1.3M
NCI NIH HHS R01 CA131164NIBIB NIH HHS R01 EB017217
6 · The paper itself

Abstract

Blood clotting is a serious clinical complication of many medical procedures and disorders including surgery, catheterization, transplantation, extracorporeal circuits, infections, and cancer. This complication leads to high patient morbidity and mortality due to clot-induced pulmonary embolism, stroke, and in some cases heart attack. Despite the clear medical significance, little progress has been made in developing the methods for detection of circulating blood clots (CBCs), also called emboli. We recently demonstrated the application of

Identifiers

PMID30460154
PMCPMC6238938
OpenAlexW2897150181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.